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- 1. Reference standards
- 2. Pharmacological research
- 3. Inhibitors
ChemFaces products have been cited in many studies from excellent and top scientific journals
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $85.5 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
- Food Funct.2022, 13(23):12105-12120.
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- Mol Neurobiol.2022, 02873-9.
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Our products had been exported to the following research institutions and universities, And still growing.
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- Lund University (Sweden)
- Gyeongsang National University (Korea)
- Ain Shams University (Egypt)
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- Int J Mol Sci.2022, 23(20):12516.
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- Biomedicines.2022, 10(3):583.
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- J Biol Chem.2021, 297(6):101362.
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- ScientificWorldJournal.2022, 2022:4806889.
- United States Patent Application2020, 20200038363
- Evid Based Complement Alternat Med.2015, 2015:165457
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan is a natural product from Saururus chinensis. |
| In vitro: |
| Biol Pharm Bull. 2008 Mar;31(3):523-6. | | Protective Effect of Lignans against Sepsis from the Roots of Saururus chinensis.[Pubmed: 18310923] |
METHODS AND RESULTS:
In the course of isolating preventive agents from sepsis based on the in vivo assay model from the EtOAc extract of the roots of Saururus chinensis, twelve lignans, sarisan (1), erythro-austrobailignan-6 (2), meso-dihydroguaiaretic acid (3), saucerneol B (4), manassantin B (5), manassantin A (6), rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan (7), (+)-saururinone (8), sauchinone (9), sauchinone B (10), nectandrin B (11) and machilin D (12), were isolated.
CONCLUSIONS:
Compounds 9 and 10, at a dose of 10 mg/kg, increased survival rates to 80% from 20% for the control experiment, and decreased the plasma levels of tumor necrosis factor-a (TNF-α) and alanine aminotransferase (ALT) activity in mice administered LPS/D-GalN.
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rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan Description
| Source: |
The fruits of Myristica fragrans |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.9377 mL |
14.6886 mL |
29.3772 mL |
58.7544 mL |
73.443 mL |
| 5 mM |
0.5875 mL |
2.9377 mL |
5.8754 mL |
11.7509 mL |
14.6886 mL |
| 10 mM |
0.2938 mL |
1.4689 mL |
2.9377 mL |
5.8754 mL |
7.3443 mL |
| 50 mM |
0.0588 mL |
0.2938 mL |
0.5875 mL |
1.1751 mL |
1.4689 mL |
| 100 mM |
0.0294 mL |
0.1469 mL |
0.2938 mL |
0.5875 mL |
0.7344 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Phytochemistry Volume 42, Issue 5, July 1996, Pages 1439–1442 | | Two lignans and an aryl alkanone from Myristica dactyloides[Reference: WebLink] |
METHODS AND RESULTS:
Chemical investigation of the hot hexane extract of the stem bark of Myristica dactyloides has resulted in the isolation of two new lignans, rel-(8S,8′R)-dimethyl-(7S,7′R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan and rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan , a new diaryl alkanone, 1-(2,6-dihydroxyphenyl)-9-(4-hydroxy-3-methoxyphenyl)nonan-1-one, sitosterol and six other previously reported aryl alkanones.
CONCLUSIONS:
The structures of the new compounds were deduced from their spectral data and chemical transformations. |
|
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