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trans-Khellactone
trans-Khellactone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name trans-Khellactone
Price:
CAS No.: 23458-04-0
Catalog No.: CFN96611
Molecular Formula: C14H14O5
Molecular Weight: 262.26 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The roots of Peucedanum wulongense.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: trans-Khellactone is a natural product from Peucedanum wulongense.
trans-Khellactone Description
Source: The roots of Peucedanum wulongense.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.813 mL 19.065 mL 38.1301 mL 76.2602 mL 95.3252 mL
5 mM 0.7626 mL 3.813 mL 7.626 mL 15.252 mL 19.065 mL
10 mM 0.3813 mL 1.9065 mL 3.813 mL 7.626 mL 9.5325 mL
50 mM 0.0763 mL 0.3813 mL 0.7626 mL 1.5252 mL 1.9065 mL
100 mM 0.0381 mL 0.1907 mL 0.3813 mL 0.7626 mL 0.9533 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2003 Sep;5(3):183-7.
Coumarins from Peucedanum wulongense.[Pubmed: 12931850]

METHODS AND RESULTS:
A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-Khellactone, was isolated from the root of Peucedanum wulongense.
CONCLUSIONS:
The structure of wulongensin A was established as 3'(R)-angeloyloxy-4'(R)-isovaleryloxy-3',4'-dihydroseselin by spectroscopic methods and the absolute configurations were deduced by chemical correlations with known compounds.
CFN98139Praeruptorin A73069-25-7386.40C21H22O7
CFN98140Praeruptorin B81740-07-0426.46C24H26O7
CFN92518Peucedanocoumarin I130464-55-0388.4C21H24O7
CFN92519Peucedanocoumarin II130464-56-1386.4C21H22O7
CFN92560Peucedanocoumarin III130464-57-2386.4C21H22O7
CFN96611trans-Khellactone23458-04-0262.26C14H14O5
CFN96610trans-Methylkhellactone23733-92-8276.28C15H16O5
CFN96612trans-3'-O-Benzoyl-4'-O-methylkhellactone23733-95-1380.39C22H20O6
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