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Natural Products
Catalog No. Information
CFN92716 Gomisin S

Reference standards.
CFN97803 Goniothalamin

Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.
CFN89238 Goshonoside F5

Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
CFN91897 Gossypetin

Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone resorption through down-regulating lysosomal cathepsin K activity and autophagy-related protein induction in actin ring-bearing osteoclasts. Gossypetin ameliorates ionizing radiation-induced oxidative stress in mice liver, it shows radioprotective action against gamma (γ)-radiation-induced oxidative stress. Gossypetin is an inducer of apoptotic and autophagic cell death in LNCaP cells, and provide a new mechanism for its anticancer activity.
CFN91987 Gossypin

Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation, carcinogenesis, and angiogenesis. Gossypin is a new hypocholesterolemic agent that up-regulates LDLR expression independent of SREBP-2 but is dependent on ERK activation. Gossypin has ameliorative effect against gentamicin-induced nephrotoxicity in rats. Gossypin also shows inhibitory effects on RANKL-induced osteoclast differentiation and bone resorption in murine macrophages (LB364).
CFN90561 Gossypol

Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.
CFN98537 Gracillin

Gracillin has anti-tumor activity, can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent.
CFN98111 Gramine

Gramine has anti-tumor, anti-viral and anti-inflammatory properties; it can activate of antioxidants and inactivative of SOD in M. aeruginosa, it also has phytotoxicity on M. aeruginosa may be due to oxidative damage via oxidation of ROS .
CFN97781 Grandiflorenic acid

Pure Grandiflorenic acid can reproduce the uterine responses induced by zoapatle leaves aqueous extract , suggests that grandiflorenic acid may have antifertility effect.
CFN97045 Grandifloroside

Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti-oxidative and anti-inflammatory agents and therapeutic agent for benign prostatic hypertrophy (BPH).