Hot Products
Catalog No. | Information |
CFN90138 | Ikarisoside F Ikarisoside F and epimedin A can bind to AdoHcy hydrolase, inhibit the activity of AdoHcy hydrolase, thus regulating the cellular biomethylation as well as reducing cellular Hcy level. |
CFN93149 | Ilexgenin A Ilexgenin A exerts anti-inflammation and anti-angiogenesis effects through inhibition of STAT3 and PI3K pathways and exhibits synergistic effects with Sorafenib on hepatoma growth. It has anti-atherosclerotic activity, it shows reduction of atherosclerosis in apolipoprotein E deficient mice. Ilexgenin A is useful in the management of cardiovascular diseases in obesity, it inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner. Ilexgenin A could be regarded as a promising agent for the treatment of melanoma, it exerts anti-melanoma activity by arresting the cell cycle at G0/G1 and regulating IL-6 and TNF-α production. |
CFN90994 | Ilexoside K Ilexoside K is a natural product from Ilex pubescens. |
CFN93153 | Ilexsaponin B2 Ilexsaponin B2 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, it is active against PDEI and PDE5A dose-dependently in vitro. |
CFN98687 | Ilicic acid Reference standards. |
CFN98758 | Imperatorin Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol); it is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. Imperatorin is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle. Imperatorin has anticonvulsant, anti-inflammatory, anti-oxidant, neuroprotection, and anti-cancer effects, it also has been used in herbal formulations for the treatment of hypertension and cardiovascular diseases. Imperatorin dampens neuronal excitability by inhibiting voltage-gated Na + channels (VGSC), and blocks the HSP27 and HSP72 gene expression. |
CFN93207 | Incensole acetate Incensole acetate is a novel anti-inflammatory compound that inhibits NF-κB activation. Incensole acetate has protective effects on cerebral ischemic injury, it can reduce depressive-like behavior and modulate hippocampal BDNF and CRF expression of submissive animals. |
CFN99501 | Indaconitine Indaconitine is a natural product from Aconitum hemsleyanum PRITZ. |
CFN00283 | Indicine Indicine N-oxide is a more active antitumor agent than its free base Indicine. |
CFN00457 | Indicine hydrochloride |