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Natural Products
Catalog No. Information
CFN70410 Hibifolin

Hibifolin can act as a potential inhibitor of ADA, it protects neurons against A beta-induced apoptosis and stimulates Akt activation, which would be useful in developing potential drugs or food supplements for treating AD. Hibifolin behaves as a dual inhibitor of PGE2 and leukotriene B4 (LTB4) formation in peritoneal exudates, thus it shows anti-inflammatory activity.
CFN99663 Hierochin D

Hierochin D is a natural product from Rehmannia glutinosa.
CFN93353 Higenamine

Higenamine (HG) is a well-known selective activator of beta2-adrenergic receptor (β2-AR) with a positive inotropic effect. HG exerts an antispasmodic effect on cold-induced vasoconstriction by regulating the PI3K/Akt, ROS/α2C-AR and PTK9 pathways independently of the AMPK/eNOS/NO axis, it reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways. HG enhances the antitumor effects of cucurbitacin B in breast cancer by inhibiting the interaction of AKT and CDK2. It attenuated LPS-induced depression-like behavior by regulating BDNF-mediated ER stress and autophagy.
CFN90698 Higenamine HCl

Higenamine HCL is derived from a wide variety of plants and works on the body as a stimulant. It specifically targets the heart muscle to speed up contractions, raising the heart rate.
CFN92007 Hinokiflavone

Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9.
CFN98948 Hinokiol

Hinokiol has anti-inflammatory activity, it has significant inhibitory effects on 5-hydroxy-eicosa-tetra-enoic acid (5-HETE) and leukotriene B(4) (LTB4) formations. Hinokiol demonstrates potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
CFN93995 Hinokitiol

Hinokitiol has antibacterial effect , it can inhibit all Staphylococcus aureus isolates with MICs of 1.56-3.13 mg/L, it also has antifungal activity against 51 Malassezia pachydermatis strains, it is an inexpensive and safe treatment with anti-inflammatory and deodorant effects that can be recommended as an effective remedy for canine otitis externa. beta-thujaplicin (Hinokitiol) has ability to extract mitochondrial Mg and the prevention of the effects of beta-thujaplicin by an excess of Mg in the medium, suggests a common mode of action of beta-thujaplicin as a lipophilic chelator of Mg and other divalent cations.
CFN98645 Hirsutanonol

Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells, it also has chemoprotective effect on human lymphocytes DNA. Hirsutanonol or oregonin as an active ingredient composition for treating atopic dermatitis, hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies.
CFN97513 Hirsutanonol 5-O-glucoside

Reference standards.
CFN90615 Hirsuteine

Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes.