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Rengynic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Rengynic acid
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CAS No.: 517883-38-4
Catalog No.: CFN98829
Molecular Formula: C8H14O4
Molecular Weight: 174.2 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The fruits of Forsythia suspensa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Rengynic acid has potent antiviral effect on RSV for the first time in vitro.
Targets: Antifection
Rengynic acid Description
Source: The fruits of Forsythia suspensa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.7405 mL 28.7026 mL 57.4053 mL 114.8106 mL 143.5132 mL
5 mM 1.1481 mL 5.7405 mL 11.4811 mL 22.9621 mL 28.7026 mL
10 mM 0.5741 mL 2.8703 mL 5.7405 mL 11.4811 mL 14.3513 mL
50 mM 0.1148 mL 0.5741 mL 1.1481 mL 2.2962 mL 2.8703 mL
100 mM 0.0574 mL 0.287 mL 0.5741 mL 1.1481 mL 1.4351 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Cell Research:
J Asian Nat Prod Res. 2014;16(4):376-82.
Two new glycosides from the fruits of Forsythia suspense.[Pubmed: 24506327]

METHODS AND RESULTS:
Two new glycosides suspensaside C (1) and 2,3,5,6-tetrahydro-jacaranone-4-O-β-D-glucopyranoside (2), together with four known compounds suspensaside A (3), Rengynic acid-1'-O-β-D-glucopyranoside (4), forsythoside A (5), and Rengynic acid (6), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HR-ESI-MS. All isolates were tested for their cytotoxicities against five human cancer cell lines (A549, Colo-205, Hep-3B, HL60, and KB).
CONCLUSIONS:
Compound 3 exhibited cytotoxicity against HL-60, Hep-3B, and A549 cancer cell lines.
Structure Identification:
J Herb Pharmacother. 2002;2(3):35-40.
A new compound from Forsythia suspensa (Thunb.) Vahl with antiviral effect on RSV.[Pubmed: 15277088]

METHODS AND RESULTS:
A new compound, 2-(1,4-dihydroxy cyclohexanyl )-acetic acid isolated from the seeds of Forsythia suspensa (Thunb.) Vahl, has been assessed for potent antiviral effect on RSV for the first time in vitro by cell morphology methods.
CONCLUSIONS:
Its structure was elucidated on the basis of spectroscopic evidence (IR, MS, 1H-NMR, 13C-NMR). We have trivially named it Rengynic acid.
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Eriodictyol

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Gypenoside L

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CAS No: 94987-09-4
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Hispidulin

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CAS No: 1447-88-7
Price: $218/20mg
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CAS No: 20633-67-4
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