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Physalin X
Physalin X
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Physalin X
Price: $318 / 5mg
CAS No.: 72497-31-5
Catalog No.: CFN95329
Molecular Formula: C28H30O10
Molecular Weight: 526.5 g/mol
Purity: > 95%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Physalis alkekengi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Physalin X exhibited inhibitory activities on NO production with IC50 values of 68.50μM.
In vitro:
Org Biomol Chem . 2017 Oct 25;15(41):8700-8704
Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309]
Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed.
Physalin X Description
Source: The herbs of Physalis alkekengi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8993 mL 9.4967 mL 18.9934 mL 37.9867 mL 47.4834 mL
5 mM 0.3799 mL 1.8993 mL 3.7987 mL 7.5973 mL 9.4967 mL
10 mM 0.1899 mL 0.9497 mL 1.8993 mL 3.7987 mL 4.7483 mL
50 mM 0.038 mL 0.1899 mL 0.3799 mL 0.7597 mL 0.9497 mL
100 mM 0.019 mL 0.095 mL 0.1899 mL 0.3799 mL 0.4748 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Org Biomol Chem. 2017 Oct 25;15(41):8700-8704.
Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential[Pubmed: 28991309]
Two novel physalins, including a 22,26-seco physalin, Physalin X (1), and a 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, aromaphysalin B (2), were isolated from Physalis angulata L. Their structures were determined by IR, UV, HRESIMS, and 2D NMR spectra as well as theoretical calculations. Compounds 1 and 2 exhibited inhibitory activities on NO production with IC50 values of 68.50 and 29.69 μM, respectively. A plausible biosynthetic pathway for 2 is also discussed.
Betaine

Catalog No: CFN99546
CAS No: 107-43-7
Price: $30/20mg
6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg
Madecassic acid

Catalog No: CFN99914
CAS No: 18449-41-7
Price: $30/20mg
Taurine

Catalog No: CFN00020
CAS No: 107-35-7
Price: $ /
Chikusetsusaponin IVa

Catalog No: CFN92516
CAS No: 51415-02-2
Price: $80/20mg
Isorhoifolin

Catalog No: CFN98927
CAS No: 552-57-8
Price: $388/20mg
Quercitrin

Catalog No: CFN98850
CAS No: 522-12-3
Price: $40/20mg
Pinocembrin 7-O-(3''-galloyl-4'',6...

Catalog No: CFN90881
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Price: $318/20mg
Gypenoside XIII

Catalog No: CFN95239
CAS No: 80325-22-0
Price: $288/10mg
Stachydrine hydrochloride

Catalog No: CFN98506
CAS No: 4136-37-2
Price: $30/20mg
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