Bioactive Products
| A unique collection of 129 Cytotoxic natural compounds used for Cytotoxic research | ||
| Catalog No: | B913 | Cytotoxic Compound Library Screening Details |
| Size: | 1mg/well * 129 Compounds 2mg/well * 129 Compounds | |
| Cat. No. | Information |
| CFN92604 | RA VII RA VII is an antitumour agent, shows cytotoxic activity against P-388 cells. RA VII causes the conformational change of F-actin and the stabilization of actin filaments to induce G2 arrest. |
| CFN92640 | Vallesiachotamine Vallesiachotamine exhibits important cytotoxicity toward human melanoma cells by apoptosis and necrosis. |
| CFN92660 | Hispidin Hispidin exhibits anti-inflammatory activity through suppressing ROS mediated NF-κB pathway in mouse macrophage cells, it also has anti-cancer activity by inducing both intrinsic and extrinsic apoptotic pathways mediated by ROS in colon cancer cells. Hispidin can inhibit Acrylamide-induced oxidative stress and protect C2C12 myotubes against palmitate-induced oxidative stress by suppressing cleavage of caspase-3, expression of Bax, and NF-κB translocation. Hispidin protects against apoptosis in H9c2 cardiomyoblast cells exposed to hydrogen peroxide through reducing intracellular ROS production, regulating apoptosis-related proteins, and the activation of the Akt/GSK-3β and ERK1/2 signaling pathways. |
| CFN92664 | Broussoflavonol F Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. Broussoflavonol F shows radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), the IC50 value of 708.54 uM. It also exhibits moderate cytotoxic activities against five human cancer cells with the IC50 value of 0.41-7.2 ug/mL. |
| CFN92693 | Coelonin Coelonin shows moderate cytotoxic activity against HepG2 cells. |
