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Bioactive Products
Neuroprotection Compound Library
A unique collection of 223 Neuroprotection natural compounds for high throughput screening (HTS)
Catalog No: B72a21 Neuroprotection Compound Library
Screening Details
Size: 1mg/well * 223 Compounds
2mg/well * 223 Compounds
Cat. No. Information
CFN00231 Tigloidine

Tigloidine hydrobromide, a naturally occuring analogue of atropine, could be as a substitute for atropine in the treatment of parkinsonism.
CFN97133 Dihydroguaiaretic acid

Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress. It shows an inhibitory effect against the complex formation of the fos-jun dimer and the DNA consensus sequence with an IC50 value of 0.21 micromol, suppresses leukemia, lung cancer and colon cancer in an in vitro bioassay. Meso-dihydroguaiaretic acid inhibits the cyclooxygenase-2 (COX-2)-dependent phase of prostaglandin D2 (PGD2) generation in bone marrow-derived mast cells (BMMC) (IC50 9.8 μM).
CFN97135 N-trans-Feruloyltyramine

N-trans-Feruloyltyramine(NTF) is a platelet aggregation inhibitor, which has hepatoprotective, and antioxidative effects, NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets;NTF inhibits melanogenesis in a dose-dependent manner.
CFN97136 Ethyl caffeate

Ethyl caffeate is a potent chemopreventive compound against skin carcinogenesis caused by solar UV exposure, it strongly inhibits neoplastic transformation of JB6 Cl41 cells without toxicity. PI3K, ERK1/2, and p38 kinase activities were suppressed by direct binding with HOEC in vitro. Ethyl caffeate also has anti-inflammatory, hepatprotective activities.
CFN97172 Sophoridine

Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis.