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1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone
1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone
Price:
CAS No.: 299895-11-7
Catalog No.: CFN92397
Molecular Formula: C18H18O6
Molecular Weight: 330.3 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Yellow powder
Source: The herbs of Cudrania cochinchinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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Biological Activity
Description: 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone is a natural product from Cudrania cochinchinensis.
In vitro:
Chem Pharm Bull (Tokyo). 2000 Aug;48(8):1219-22.
Studies on the constituents of Anaxagorea luzonensis A. GRAY.[Pubmed: 10959592]

METHODS AND RESULTS:
Five new xanthones, 1,3,6-trihydroxy-5-methoxy-4-prenylxanthone (1), 1,3,5-trihydroxy-6-methoxy-2-prenylxanthone (2), 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone (3), 1,3,6-trihydroxy-4-prenylxanthone (4), 3,6-dihydroxy-1,5-dimethoxyxanthone (5) and one new flavonoid, 3,5,7,4'-tetrahydroxy-2'-methoxyflavone (6) along with seven known xanthones and seven known flavonoids were isolated from the bark of Anaxagorea luzonensis A. GRAY and their chemical structures were determined by means of chemical and spectral studies.
CONCLUSIONS:
Almost all flavonoids and one xanthone (13) showed antioxidant activity.
1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone Description
Source: The herbs of Cudrania cochinchinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0276 mL 15.1378 mL 30.2755 mL 60.551 mL 75.6888 mL
5 mM 0.6055 mL 3.0276 mL 6.0551 mL 12.1102 mL 15.1378 mL
10 mM 0.3028 mL 1.5138 mL 3.0276 mL 6.0551 mL 7.5689 mL
50 mM 0.0606 mL 0.3028 mL 0.6055 mL 1.211 mL 1.5138 mL
100 mM 0.0303 mL 0.1514 mL 0.3028 mL 0.6055 mL 0.7569 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):393-7.
Xanthones from the roots of Cudrania fruticosa Wight.[Pubmed: 17613626 ]

METHODS AND RESULTS:
Chemical investigation on the roots of Cudrania fruticosa resulted in the isolation of two new xanthones, 1,6,7-trihydroxy-2-(1,1-dimethyl-2-propenyl)-3-methoxyxanthone (1) and 3,6,7-trihydroxy-1-methoxyxanthone (2), together with three known ones, 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone (3), 1,3-dihydroxy-6,7-dimethoxyxanthone (4) and 3,5,6-trihydroxy-1-methoxyxanthone (5), respectively.
CONCLUSIONS:
Their structures were elucidated on the basis of spectral and chemical techniques.
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