1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone | CAS:776325-66-7

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

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Product Name	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
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CAS No.:	776325-66-7
Catalog No.:	CFN97260
Molecular Formula:	C₂₃H₂₄O₆
Molecular Weight:	396.4 g/mol
Purity:	>=98%
Type of Compound:	Xanthones
Physical Desc.:	Yellow powder
Source:	The herbs of Garcinia xanthochymus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.

In vitro:

Chem Biodivers. 2007 May;4(5):940-6.

Cytotoxic prenylated phenolic compounds from the twig bark of Garcinia xanthochymus.[Pubmed: 17511007]

METHODS AND RESULTS:
Three new hydroxylated xanthones with prenyl or geranyl substituents, compounds 1-3, were isolated from the twig bark of Garcinia xanthochymus, along with the four known compounds 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone (4), 1,3,5,6-tetrahydroxy-4,7,8-triprenylxanthone (5), garciniaxanthone E (6), and 6-prenylapigenin (7). Their structures were elucidated by extensive spectroscopic analysis, including 1D- and 2D-NMR as well as HR-MS experiments.
CONCLUSIONS:
All compounds showed moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacked antifungal activity against Candida albicans.

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone Description

Source:	The herbs of Garcinia xanthochymus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Xanthones Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5227 mL	12.6135 mL	25.227 mL	50.4541 mL	63.0676 mL
5 mM	0.5045 mL	2.5227 mL	5.0454 mL	10.0908 mL	12.6135 mL
10 mM	0.2523 mL	1.2614 mL	2.5227 mL	5.0454 mL	6.3068 mL
50 mM	0.0505 mL	0.2523 mL	0.5045 mL	1.0091 mL	1.2614 mL
100 mM	0.0252 mL	0.1261 mL	0.2523 mL	0.5045 mL	0.6307 mL

CFN89085	Pancixanthone A	174232-30-5	312.32	C₁₈H₁₆O₅
CFN89134	Isocudraniaxanthone A	197447-26-0	328.32	C₁₈H₁₆O₆
CFN96577	Isocudraniaxanthone B	199851-52-0	342.35	C₁₉H₁₈O₆
CFN97410	Cudraxanthone B	84955-05-5	394.4	C₂₃H₂₂O₆
CFN89371	Cudratricusxanthone A	740810-42-8	396.43	C₂₃H₂₄O₆
CFN97543	Cudraxanthone D	96552-41-9	410.5	C₂₄H₂₆O₆
CFN92090	Toxyloxanthone D	50906-63-3	396.4	C₂₃H₂₄O₆
CFN99422	Cudraxanthone L	135541-40-1	396.4	C₂₃H₂₄O₆
CFN97260	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone	776325-66-7	396.4	C₂₃H₂₄O₆
CFN89050	Formoxanthone A	869880-32-0	394.42	C₂₃H₂₂O₆