Science | Nature | Cell | View More
Natural Products
1,5,6-Trihydroxy-3-methoxyxanthone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1,5,6-Trihydroxy-3-methoxyxanthone
Price:
CAS No.: 50868-52-5
Catalog No.: CFN89549
Molecular Formula: C14H10O6
Molecular Weight: 274.22 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The herbs of Mangifera indica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Donald Danforth Plant Science C... (USA)
  • Universidade da Beira Interior (Germany)
  • The Ohio State University (USA)
  • Pennsylvania State University (USA)
  • Heinrich-Heine-University Düss... (Germany)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Chiang Mai University (Thailand)
  • The University of Newcastle (Australia)
  • Universidade Federal de Pernamb... (Brazil)
  • Universidad Veracuzana (Mexico)
  • University of Wollongong (Australia)
  • More...
Package
Featured Products
Ganoderic acid B

Catalog No: CFN92052
CAS No: 81907-61-1
Price: $288/20mg
Parishin C

Catalog No: CFN93114
CAS No: 174972-80-6
Price: $188/20mg
Isocorynoxeine

Catalog No: CFN98155
CAS No: 51014-29-0
Price: $128/20mg
Epicatechin

Catalog No: CFN98781
CAS No: 490-46-0
Price: $40/20mg
Ganoderic acid D

Catalog No: CFN90292
CAS No: 108340-60-9
Price: $338/20mg
1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg
Loliolid

Catalog No: CFN92750
CAS No: 5989-02-6
Price: $318/5mg
Bakuchalcone

Catalog No: CFN92229
CAS No: 84575-13-3
Price: $ / mg
Didymin

Catalog No: CFN92363
CAS No: 14259-47-3
Price: $80/20mg
Acanthoside B

Catalog No: CFN97220
CAS No: 7374-79-0
Price: $268/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
Targets: ROS
In vitro:
Food Science & Biotechnology, 2013, 22(4):945-949.
Isolation of xanthones from adventitious roots of St. John’s Wort (Hypericum perforatum L.) and their antioxidant and cytotoxic activities.[Reference: WebLink]

METHODS AND RESULTS:
In this phytochemical study, 5 xanthones, 1,3,5,6-tetrahydroxyxanthone [1], 1,5,6-Trihydroxy-3-methoxyxanthone [2], ferrxanthone [3], brasilixanthone B [4], and neolancerin [5] were isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.). Compound 1–5 were evaluated for antioxidant activities using the intracellular reactive oxygen species (ROS) radical scavenging 2′,7′-dichlorfluorescein-diacetate (DCFDA) assay and for cytotoxic activity against the HL-60 human promyelocytic leukemia cells.
CONCLUSIONS:
Among them, compound 1–4 exhibited scavenging activity with inhibition values of 27.4–33.2% at 10 μM; compound 1, 2, and 4 reduced the viability of HL-60 cells significantly, with IC50 values of 31.5, 28.9, and 27.7 μM, respectively.
1,5,6-Trihydroxy-3-methoxyxanthone Description
Source: The herbs of Mangifera indica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Formononetin-8-C-beta-D-apiofurano...

Catalog No: CFN95157
CAS No: 1147858-78-3
Price: $318/10mg
Peiioside B

Catalog No: CFN95336
CAS No: 1610618-91-1
Price: $318/5mg
Epischisandrone

Catalog No: CFN95212
CAS No: 98619-26-2
Price: $413/5mg
Maingayone

Catalog No: CFN95479
CAS No: 271585-66-1
Price: $318/10mg
New compound 5

Catalog No: CFN95258
CAS No: N/A
Price: $413/5mg
Neoorthosiphol A

Catalog No: CFN95447
CAS No: 243448-72-8
Price: $318/10mg
Leachianol F

Catalog No: CFN95147
CAS No: 164123-50-6
Price: $318/5mg
(3E,5E,11E)-tridecatriene-7,9-diyn...

Catalog No: CFN95191
CAS No: 94753-06-7
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6467 mL 18.2335 mL 36.4671 mL 72.9341 mL 91.1677 mL
5 mM 0.7293 mL 3.6467 mL 7.2934 mL 14.5868 mL 18.2335 mL
10 mM 0.3647 mL 1.8234 mL 3.6467 mL 7.2934 mL 9.1168 mL
50 mM 0.0729 mL 0.3647 mL 0.7293 mL 1.4587 mL 1.8234 mL
100 mM 0.0365 mL 0.1823 mL 0.3647 mL 0.7293 mL 0.9117 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Ganoderic acid B

Catalog No: CFN92052
CAS No: 81907-61-1
Price: $288/20mg
Parishin C

Catalog No: CFN93114
CAS No: 174972-80-6
Price: $188/20mg
Isocorynoxeine

Catalog No: CFN98155
CAS No: 51014-29-0
Price: $128/20mg
Epicatechin

Catalog No: CFN98781
CAS No: 490-46-0
Price: $40/20mg
Ganoderic acid D

Catalog No: CFN90292
CAS No: 108340-60-9
Price: $338/20mg
1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg
Loliolid

Catalog No: CFN92750
CAS No: 5989-02-6
Price: $318/5mg
Bakuchalcone

Catalog No: CFN92229
CAS No: 84575-13-3
Price: $ / mg
Didymin

Catalog No: CFN92363
CAS No: 14259-47-3
Price: $80/20mg
Acanthoside B

Catalog No: CFN97220
CAS No: 7374-79-0
Price: $268/20mg
Tags: buy 1,5,6-Trihydroxy-3-methoxyxanthone | 1,5,6-Trihydroxy-3-methoxyxanthone supplier | purchase 1,5,6-Trihydroxy-3-methoxyxanthone | 1,5,6-Trihydroxy-3-methoxyxanthone cost | 1,5,6-Trihydroxy-3-methoxyxanthone manufacturer | order 1,5,6-Trihydroxy-3-methoxyxanthone | 1,5,6-Trihydroxy-3-methoxyxanthone distributor