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1,7-Dihydroxyacridone
1,7-Dihydroxyacridone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1,7-Dihydroxyacridone
Price:
CAS No.: 112649-95-3
Catalog No.: CFN96973
Molecular Formula: C13H9NO3
Molecular Weight: 227.21 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Boenninghausenia albiflora.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 1,7-Dihydroxyacridone is a natural product from Boenninghausenia albiflora.
1,7-Dihydroxyacridone Description
Source: The herbs of Boenninghausenia albiflora.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4012 mL 22.0061 mL 44.0121 mL 88.0243 mL 110.0304 mL
5 mM 0.8802 mL 4.4012 mL 8.8024 mL 17.6049 mL 22.0061 mL
10 mM 0.4401 mL 2.2006 mL 4.4012 mL 8.8024 mL 11.003 mL
50 mM 0.088 mL 0.4401 mL 0.8802 mL 1.7605 mL 2.2006 mL
100 mM 0.044 mL 0.2201 mL 0.4401 mL 0.8802 mL 1.1003 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Supplements to Edition of Rodds Chemistry of Carbon Compounds, 1975:245-258.
Sainsbury M. Chapter 32–The acridine alkaloids.[Reference: WebLink]
This chapter provides an overview of the acridine alkaloids. Gravacridone triol represents a new alkaloid from Ruta graveolens, where it co-occurs with its monoglucosyl derivative and the glucoside of a known alkaloid gravacridone diol.
METHODS AND RESULTS:
The 5-hydroxy derivative of the known alkaloid arborinine has been obtained for the first time from the leaves of Glycosmis bilocularis. Two other acridones differing only in the presence or absence of methoxyl groups are the alkaloids and isolated from the leaves of Bauerella simplicifolia. Boenninghausenia albiflora produces 1-hydroxyacridone and possibly also 1,7-Dihydroxyacridone.
CONCLUSIONS:
Two new acridones, 1-hydroxy-3,4-dimethoxy-10-methylacridone and l-hydroxy-3-geranyloxy-4-methoxy-10-methylacridone occur in extracts of the plant Sarcomelicope leiocarpa indigenous to New Caledonia together with eight other known structures. Another series of related alkaloids are produced by the plant Glycosmis citrifolia; these include the acridones glycocitrine-I, glycocitrine-II, its o-methyl ether, glyfoline, furofoline-II, and pyranofoline.
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