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1-Methoxyindole-3-carboxylic acid
1-Methoxyindole-3-carboxylic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Methoxyindole-3-carboxylic acid
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CAS No.: 91913-76-7
Catalog No.: CFN96036
Molecular Formula: C10H9NO3
Molecular Weight: 191.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Isatis indigotica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Xenobiotica. 1991 May;21(5):569-74.
In vitro O-demethylation from a heterocyclic nitrogen: a novel metabolic reaction?[Pubmed: 1949889]

METHODS AND RESULTS:
1. O-Demethylation of 1-Methoxyindole-3-carboxylic acid, in vitro, by determination of liberated formaldehyde, has been demonstrated using fortified 15,000 g rat liver supernatant fraction. 2. Results have been compared to those similarly obtained with a standard O-demethylation substrate, 4-nitroanisole, to substantiate and quantify the extent of the reaction. 3. Km values for 4-nitroanisole and methoxyindole-3-carboxylic acid were 8.9 and 6.5 mM, while Vmax values were 4.9, and 5.2 nmol HCHO produced/mg protein per min.
CONCLUSIONS:
4. The significance of the metabolic O-demethylation reaction for N-methoxyindoles as a novel metabolic pathway is discussed in terms of pharmacological activity and biological reactivity.
1-Methoxyindole-3-carboxylic acid Description
Source: The herbs of Isatis indigotica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2301 mL 26.1506 mL 52.3013 mL 104.6025 mL 130.7531 mL
5 mM 1.046 mL 5.2301 mL 10.4603 mL 20.9205 mL 26.1506 mL
10 mM 0.523 mL 2.6151 mL 5.2301 mL 10.4603 mL 13.0753 mL
50 mM 0.1046 mL 0.523 mL 1.046 mL 2.0921 mL 2.6151 mL
100 mM 0.0523 mL 0.2615 mL 0.523 mL 1.046 mL 1.3075 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Europine

Catalog No: CFN00264
CAS No: 570-19-4
Price: $ /
Sinigrin

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6-Methoxyluteolin

Catalog No: CFN92706
CAS No: 520-11-6
Price: $268/20mg
Isovalerylshikonin

Catalog No: CFN95222
CAS No: 52387-14-1
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Ganoderenic acid D

Catalog No: CFN90300
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Allicin

Catalog No: CFN90201
CAS No: 539-86-6
Price: $50/20mg
Silymarin

Catalog No: CFN99542
CAS No: 22888-70-6
Price: $30/20mg
Vanillic acid

Catalog No: CFN99331
CAS No: 121-34-6
Price: $30/20mg
Pueroside A

Catalog No: CFN95177
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Gelsemine

Catalog No: CFN99001
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Price: $218/20mg
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