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11-Hydroxycodaphniphylline
11-Hydroxycodaphniphylline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 11-Hydroxycodaphniphylline
Price:
CAS No.: 1186496-68-3
Catalog No.: CFN99284
Molecular Formula: C30H47NO4
Molecular Weight: 485.7 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Daphniphyllum subverticillatum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
J Nat Prod. 2009 Sep;72(9):1669-72.
Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed: 19739650]

METHODS AND RESULTS:
Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-Hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence.
CONCLUSIONS:
Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC(50) values in the range 2.4-9.7 microM and against the HMEC human microvascular endothelial cell line with an IC(50) of 2.7 microM.
11-Hydroxycodaphniphylline Description
Source: The leaves of Daphniphyllum subverticillatum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0589 mL 10.2944 mL 20.5888 mL 41.1777 mL 51.4721 mL
5 mM 0.4118 mL 2.0589 mL 4.1178 mL 8.2355 mL 10.2944 mL
10 mM 0.2059 mL 1.0294 mL 2.0589 mL 4.1178 mL 5.1472 mL
50 mM 0.0412 mL 0.2059 mL 0.4118 mL 0.8236 mL 1.0294 mL
100 mM 0.0206 mL 0.1029 mL 0.2059 mL 0.4118 mL 0.5147 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97484Daphnilongeridine922522-15-4513.8 C32H51NO4
CFN98003Daphmacrine19775-48-5511.8 C32H49NO4
CFN98270Daphnezomine B247078-43-9375.6 C23H37NO3
CFN98629Daphmacropodine39729-21-0513.8 C32H51NO4
CFN99061Yunnandaphninine G1042143-83-8469.7 C30H47NO3
CFN9928411-Hydroxycodaphniphylline1186496-68-3485.7 C30H47NO4
CFN99608Codaphniphylline14694-15-6469.7 C30H47NO3
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