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11-Hydroxycanthin-6-one
11-Hydroxycanthin-6-one
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 11-Hydroxycanthin-6-one
Price: $413 / 5mg
CAS No.: 75969-83-4
Catalog No.: CFN92125
Molecular Formula: C14H8N2O2
Molecular Weight: 236.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Yellow powder
Source: The barks of Picrasma quassioides (D.Don) Benn
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 11-Hydroxy-canthin-6-one has antineoplastic activity.
11-Hydroxycanthin-6-one Description
Source: The barks of Picrasma quassioides (D.Don) Benn
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2337 mL 21.1685 mL 42.337 mL 84.674 mL 105.8425 mL
5 mM 0.8467 mL 4.2337 mL 8.4674 mL 16.9348 mL 21.1685 mL
10 mM 0.4234 mL 2.1169 mL 4.2337 mL 8.4674 mL 10.5843 mL
50 mM 0.0847 mL 0.4234 mL 0.8467 mL 1.6935 mL 2.1169 mL
100 mM 0.0423 mL 0.2117 mL 0.4234 mL 0.8467 mL 1.0584 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 1988, 44(11):3349-54.
Antineoplastic agents 157. Quassia kerstingII1[Reference: WebLink]
The oxacanthin alkaloid components of Quassia kerstingü L. have been found to be 2-hydroxy- and 11-Hydroxycanthin-6-one (1a and 1b).
METHODS AND RESULTS:
Structure 1a was confirmed by results of methylation (1a → 1c + 2a) and NOE studies. A selective INEPT NMR technique was employed to support unequivocally the 11-Hydroxycanthin-6-one (1b) assignment.
CFN98730Canthin-6-one479-43-6220.2 C14H8N2O
CFN92010Canthin-6-one N-oxide60755-87-5236.2C14H8N2O2
CFN972871-Hydroxycanthin-6-one80787-59-3236.2 C14H8N2O2
CFN921269-Hydroxycanthin-6-one138544-91-9236.2C14H8N2O2
CFN9401210-Hydroxycanthin-6-one86293-41-6236.23C14H8N2O2
CFN920119-Methoxycanthin-6-one74991-91-6250.3C15H10N2O2
CFN920129-Methoxycanthin-6-one-N-oxide137739-74-3266.3C15H10N2O3
CFN921241-Hydroxy-9-medroxycanthin-6-one622408-85-9266.3C15H10N2O3
CFN9212511-Hydroxycanthin-6-one75969-83-4236.2C14H8N2O2
CFN921279,10-Dimethoxycanthin-6-one155861-51-1280.3C16H12N2O3
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