Structure Identification: |
Lishizhen Medicine & Materia Medica Research, 2009 , 20 (2) :267-270. | Study on the Cycloartane Triterpenes of Actaea asiatiea.[Reference: WebLink] | To isolate and elucidate the constituents of Actaea asiatiea. METHODS AND RESULTS: Chemical constituents were isolated by repeated column chromatography(Toyopearl HW-40C and preparative HPLC) and their structures were elucidated on the basis of spectral data analysis. Fifteen cycloartane triterpenes were isolated from Actaea asiatiea,asiaticoside A,asiaticoside B,26-deoxycimicifugoside,Cimicifugoside(23S),25-O-methylcimigenol-3-O-beta-D-xylopyranoside,25,2′-O-diacetylcimigenol-3-O-β-D-xylopyranoside,24-O-acetylshengmanol-3-O-β-D-xylopyranoside(23R,24R),24-O-acetyldahurinol-3-O-β-D-xylopyranoside,23-O-acetylshengmanol-3-O-β-D-xylopyranoside,CimiracemosideM,12β-acetoxy-3β-hydroxy-24,25,26,27-tetranor-cycloart-7-en-23,16β-olide-3-O-β-D-xylopyranoside,12β-acetoxy-3β-hydroxy-24,25,26,27-tetranor-cycloartan-23,16β-olide-3-O-β-D-xylopyranoside,Cimiracemoside H,Neocimicigenosides B,2′-O-acetyl-25-anhydrocimigenol-3-O-β-D-xylopyranoside. CONCLUSIONS: Compound 3~15 were first isolated from Actaea asiatiea. |
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