3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid | CAS:36138-41-7

3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid

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Product Name	3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid
Price:
CAS No.:	36138-41-7
Catalog No.:	CFN96940
Molecular Formula:	C₃₀H₄₆O₄
Molecular Weight:	470.69 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The leaves and twigs of Lithocarpus litseifolius.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid exhibits potent inhibition of superoxide-anion generation with 86.9 ± 2.8% inhibition at 1 uM.

In vitro:

Planta Med. 2017 Jul 12.

Bioactive Triterpenoids from the Leaves and Twigs of Lithocarpus litseifolius and L. corneus.[Pubmed: 28701018]

METHODS AND RESULTS:
Phytochemical investigation of the leaves and twigs of Lithocarpus litseifolius and Lithocarpus corneus resulted in the isolation of four new triterpenoids (1-4), three triterpenoids (5-7) isolated from a natural source for the first time, and six known compounds (8-13). In addition, four known triterpenoids (14-17) were isolated from L. corneus. Compound 1 is a 3,4-seco-lupane-type triterpenoid, and compounds 2-4 are lupane-type triterpenoids in different oxidation states. The structures of all isolated compounds were identified by spectroscopic methods, especially NMR and mass spectrometry data. The absolute configuration of 2 and 3 was confirmed by X-ray single crystallographic analysis. The anti-inflammatory activities of 1-17 and anti-HIV activities of 2-17 were evaluated.
CONCLUSIONS:
Among them, 3-epi-betulinic acid (8) showed a strong anti-HIV activity comparable to abacavir, a drug used for treating HIV/AIDS. 3,4-seco-4(23),20(29)-lupadiene-3,28-dioic acid (3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid ,5) exhibited potent inhibition of superoxide-anion generation with 86.9 ± 2.8% inhibition at 1 μM.

3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid Description

Source:	The leaves and twigs of Lithocarpus litseifolius.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1245 mL	10.6227 mL	21.2454 mL	42.4908 mL	53.1135 mL
5 mM	0.4249 mL	2.1245 mL	4.2491 mL	8.4982 mL	10.6227 mL
10 mM	0.2125 mL	1.0623 mL	2.1245 mL	4.2491 mL	5.3114 mL
50 mM	0.0425 mL	0.2125 mL	0.4249 mL	0.8498 mL	1.0623 mL
100 mM	0.0212 mL	0.1062 mL	0.2125 mL	0.4249 mL	0.5311 mL

CFN98072	1-Decarboxy-3-oxo-ceanothic acid	214150-74-0	440.7	C₂₉H₄₄O₃
CFN98063	Ceanothic acid	21302-79-4	486.7	C₃₀H₄₆O₅
CFN99309	Ceanothic acid acetate	119533-63-0	528.7	C₃₂H₄₈O₆
CFN96940	3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid	36138-41-7	470.69	C₃₀H₄₆O₄
CFN90571	Chiisanoside	89354-01-8	955.10	C₄₈H₇₄O₁₉