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3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
Price:
CAS No.: 244277-75-6
Catalog No.: CFN96297
Molecular Formula: C34H43NO11
Molecular Weight: 641.7 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Euphorbia kansui.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
Targets: Trk receptor
In vitro:
J Nat Prod. 2004 Sep;67(9):1548-51.
Activity of macrocyclic jatrophane diterpenes from Euphorbia kansui in a TrkA fibroblast survival assay.[Pubmed: 15387657 ]

METHODS AND RESULTS:
Three new macrocyclic diterpenes, kansuinins F (1), G (2), and H (3), together with four known jatrophane diterpenes, kansuinins D (4), E (5), and A (6) and 3beta,5alpha,7beta,15beta-tetraacetoxy-9alpha-nicotinoyloxyjatropha-6(17)-11E-dien-14-one(3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one), were isolated from the roots of Euphorbia kansui. Compounds 1 and 2 were assigned as 6(17)-en-11,12-epoxy-14-one-type jatrophane diterpenes, and compound 3 as a 6(17)-en-11,14-epoxy-12-one jatrophane diterpene. The structures of compounds 1-3 and the relative configurations of compounds 4 and 5 were determined by spectral data analysis.
CONCLUSIONS:
Kansuinin E (5) exhibited a specific survival effect on fibroblasts that expressed TrkA, a high-affinity receptor for nerve growth factor.
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one Description
Source: The roots of Euphorbia kansui.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5584 mL 7.7918 mL 15.5836 mL 31.1672 mL 38.959 mL
5 mM 0.3117 mL 1.5584 mL 3.1167 mL 6.2334 mL 7.7918 mL
10 mM 0.1558 mL 0.7792 mL 1.5584 mL 3.1167 mL 3.8959 mL
50 mM 0.0312 mL 0.1558 mL 0.3117 mL 0.6233 mL 0.7792 mL
100 mM 0.0156 mL 0.0779 mL 0.1558 mL 0.3117 mL 0.3896 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Loganin

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CAS No: 18524-94-2
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N-p-trans-Coumaroyltyramine

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CAS No: 36417-86-4
Price: $268/10mg
Acteoside

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CAS No: 61276-17-3
Price: $60/20mg
Abietic acid

Catalog No: CFN90587
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Price: $40/20mg
Oxymatrine

Catalog No: CFN99805
CAS No: 16837-52-8
Price: $40/20mg
Rosavin

Catalog No: CFN99179
CAS No: 84954-92-7
Price: $68/20mg
Cryptotanshinone

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Beta-Carotene

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8-Prenylkaempferol

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Brusatol

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