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3-Nitro-L-tyrosine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3-Nitro-L-tyrosine
Price: $30 / 20mg
CAS No.: 621-44-3
Catalog No.: CFN90054
Molecular Formula: C9H10N2O5
Molecular Weight: 226.19 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: From Chemical synthesis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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Biological Activity
Description: 3-Nitro-L-tyrosine,an oxidative stress marker associated with neurodegenerative disorders.3-Nitro-L-tyrosine could as solid-phase extraction (SPE) sorbent material.
3-Nitro-L-tyrosine Description
Source: From Chemical synthesis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4211 mL 22.1053 mL 44.2106 mL 88.4212 mL 110.5265 mL
5 mM 0.8842 mL 4.4211 mL 8.8421 mL 17.6842 mL 22.1053 mL
10 mM 0.4421 mL 2.2105 mL 4.4211 mL 8.8421 mL 11.0527 mL
50 mM 0.0884 mL 0.4421 mL 0.8842 mL 1.7684 mL 2.2105 mL
100 mM 0.0442 mL 0.2211 mL 0.4421 mL 0.8842 mL 1.1053 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Biosens Bioelectron. 2013 Feb 15;40(1):336-41.
Developments in the synthesis of a water compatible molecularly imprinted polymer as artificial receptor for detection of 3-nitro-L-tyrosine in neurological diseases.[Pubmed: 22922080]
A highly selective water compatible molecularly imprinted polymer (MIP) for 3-Nitro-L-tyrosine (3NT), an oxidative stress marker associated with neurodegenerative disorders, was prepared and its use as solid-phase extraction (SPE) sorbent material was demonstrated. The MIP was prepared by bulk polymerization using methacrylic acid as functional monomer and acetonitrile as porogen with traces of acetic acid and trifluoroacetic acid.
METHODS AND RESULTS:
In order to evaluate its binding properties, the MIP was analyzed by batch rebinding experiments and subsequently used as SPE sorbent for the selective clean-up and pre-concentration of 3-Nitro-L-tyrosine from standard solutions and spiked human urine samples. The results obtained from batch rebinding experiments showed the presence of two association constants corresponding to high-affinity (Ka 4.20×10(3) M(-1)) and low-affinity (Ka 0.79×10(3) M(-1)) binding sites. Standard mixture solution loaded on MIP-SPE cartridge gave a recovery of 95% for 3-Nitro-L-tyrosine , while the other compounds were totally eluted during washing step. Percentage of recovery higher than 90%, with relative standard deviation of 2%, was also obtained when a maximum of 55 μg of 3NT is used in spiked urine sample and loaded into the cartridge.
CONCLUSIONS:
Validation of the analytical method for 3-Nitro-L-tyrosine quantification in human urine gave 0.7 μg mL(-1) of limit of detection, a linear range of 2.5-55 μg mL(-1) with a relative standard deviation of 2%.
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Licochalcone D

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Echinacoside

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Price: $30/20mg
Morusin

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CAS No: 62596-29-6
Price: $128/20mg
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