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3-beta-O-(cis-p-Coumaroyl)maslinic acid
3-beta-O-(cis-p-Coumaroyl)maslinic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3-beta-O-(cis-p-Coumaroyl)maslinic acid
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CAS No.: 69297-40-1
Catalog No.: CFN92208
Molecular Formula: C39H54O6
Molecular Weight: 618.9 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: From Faeces Trogopterpri
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 3-beta-O-(trans-p-Coumaroyl)maslinic acid shows antimicrobial activity on Gram-positive bacteria and yeasts.
In vitro:
Planta Medica, 2000, 66(8):768-769.
Antimicrobial Triterpenoids from Licania heteromorpha.[Reference: WebLink]

METHODS AND RESULTS:
Six triterpenoids having a lupane and oleane skeleton were isolated from the leaves and young branches of Licania heteromorpha Bentham var. heteromorpha and were identified as: betulinic acid 1, alphitolic acid 2, 3 beta-O-trans-p-coumaroyl alphitolic acid 3, 3 beta-O-cis-p-coumaroyl alphitolic acid 4, 3 beta-O-trans-p-coumaroyl maslinic acid 5, 3-beta-O-(cis-p-Coumaroyl)maslinic acid 6. The antimicrobial activity of these compounds was evaluated in vitro on clinically isolated microorganisms employing a microdilution method.
CONCLUSIONS:
Compounds 2, 3, 5, and 6 showed antimicrobial activity on Gram-positive bacteria and yeasts, whereas none of the six triterpenoids were active against Gram-negative organisms.
3-beta-O-(cis-p-Coumaroyl)maslinic acid Description
Source: From Faeces Trogopterpri
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6158 mL 8.0788 mL 16.1577 mL 32.3154 mL 40.3942 mL
5 mM 0.3232 mL 1.6158 mL 3.2315 mL 6.4631 mL 8.0788 mL
10 mM 0.1616 mL 0.8079 mL 1.6158 mL 3.2315 mL 4.0394 mL
50 mM 0.0323 mL 0.1616 mL 0.3232 mL 0.6463 mL 0.8079 mL
100 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.3232 mL 0.4039 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Pharmaceutical Journal,2010,45(11):825-828.
Isolation and identification of 3-O-p-coumaroyloxyl pentacyclic triterpenoids from Lysimachia clethroides Duby.[Reference: WebLink]
To isolate and identify the 3-O-p-coumaroyloxyl pentacyclic triterpenoids from acetoacetate extract of Lysimachia clethroides Duby, which showed significant cancer chemopreventive activities.
METHODS AND RESULTS:
The 3-O-p-coumaroyloxyl pentacyclic triterpenoids were isolated by using silica gel column chromatography, Sephadex LH - 20 chromatography MPLC, and Semi-HPLC. Their structures were elucidated with spectroscopic analysis (NMR, MS and IR). Six 3-O-p-coumaroyloxyl pentacyclic triterpenoids were isolated and identified as 3-beta-O-(cis-p-Coumaroyl)maslinic acid(I), 3-O-trans-p-coumaroyl maslinic acid (II), 3-O-cis-p-coumaroyl-2α-hydroxyursolic acid (III), 3-O-trans-p-coumaroyl-2α-hydroxyursolic acid (IV), 3-O-cis-p-coumaroyl tormentic acid (V) and 3-O-trans-p-coumaroyl tormentic acid (VI).
CONCLUSIONS:
All these compounds were obtained from the Lysimachia Genus for the first time.
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