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- 3. Inhibitors
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan
ChemFaces products have been cited in many studies from excellent and top scientific journals
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Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
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Our products had been exported to the following research institutions and universities, And still growing.
- Utrecht University (Netherlands)
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- Kazusa DNA Research Institute (Japan)
- Chulalongkorn University (Thailand)
- Macau University of Science and... (China)
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Related Screening Libraries
Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
Description: |
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan shows cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15). |
In vitro: |
Arch Pharm Res. 2013 Oct;36(10):1211-4. | Cytotoxic lignans from Viburnum foetidum.[Pubmed: 23881703 ] | METHODS AND RESULTS: Two new lignans, 3,4,4'-trihydroxy-3',9-dimethoxy-9,9'-epoxylignan (1), 3,4'-dihydroxy-3',4, 9-trimethoxy-9,9'-epoxylignan (2), together with one known compound, 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan (3), were isolated from the 95 % EtOH extract of Viburnum foetidum. The structures of the two new compounds were elucidated on the basis of 1D, 2D-NMR, and mass spectral analysis.
CONCLUSIONS:
All the lignans were in vitro evaluated for their cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15). |
|
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan Description
Source: |
The herbs of Viburnum foetidum. |
Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
2.6707 mL |
13.3536 mL |
26.7073 mL |
53.4145 mL |
66.7682 mL |
5 mM |
0.5341 mL |
2.6707 mL |
5.3415 mL |
10.6829 mL |
13.3536 mL |
10 mM |
0.2671 mL |
1.3354 mL |
2.6707 mL |
5.3415 mL |
6.6768 mL |
50 mM |
0.0534 mL |
0.2671 mL |
0.5341 mL |
1.0683 mL |
1.3354 mL |
100 mM |
0.0267 mL |
0.1335 mL |
0.2671 mL |
0.5341 mL |
0.6677 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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