6-Hydroxykaempferol-3,6,7-triglucoside | CAS:145134-62-9

6-Hydroxykaempferol-3,6,7-triglucoside

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Description:

6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.

In vitro:

Natural Med., 2005, 59(5):241-4.

Antiplatelet Aggregatory Effects of the Constituents Isolated from the Flower of Cartham.ua tinctorius[Reference: WebLink]

METHODS AND RESULTS:
Four constituents, 6-Hydroxykaempferol 3,6,7-trr-O-glucoside ( 6-Hydroxykaempferol-3,6,7-triglucoside,1 ) , 6-hydroxykaempferol 3-Orutinoside-6-0-glucoside (2), 6'hydroxykaempferol 3,6-dr0-glueoside (3), and syringin (4) were isolated from the flower of Carthamus tinctorius L. and were examined for the inhibitory effects on platelet aggregation. The platelet aggregation was monitored by a platelet aggregometer employing a laser-scattering method. The compounds were identified on the basis of NMR spectral data.
CONCLUSIONS:
Compound 1, 3 and 4 inhibited platelet aggregation induced by collagen. Compound 4 also showed an antiplatelet aggregatory effect when the platelet aggregation was induced by adenosine 5'-diphosphate (ADP). However, 2 showed no inhibitory effect on platelet aggregation induced by collagen or ADP. Furthermore, 1 and 3 showed weak inhibitory effects on the ADP-induced platelet aggregation.

6-Hydroxykaempferol-3,6,7-triglucoside Description

Source:	The herbs of Chrysactinia tinctorius
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	6-Hydroxykaempferol-3,6,7-triglucoside
Price:
CAS No.:	145134-62-9
Catalog No.:	CFN92521
Molecular Formula:	C₃₃H₄₀O₂₂
Molecular Weight:	788.7 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Chrysactinia tinctorius
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-platelet aggregation Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.2679 mL	6.3395 mL	12.6791 mL	25.3582 mL	31.6977 mL
5 mM	0.2536 mL	1.2679 mL	2.5358 mL	5.0716 mL	6.3395 mL
10 mM	0.1268 mL	0.634 mL	1.2679 mL	2.5358 mL	3.1698 mL
50 mM	0.0254 mL	0.1268 mL	0.2536 mL	0.5072 mL	0.634 mL
100 mM	0.0127 mL	0.0634 mL	0.1268 mL	0.2536 mL	0.317 mL

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