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7-Acetylscorpioidine
7-Acetylscorpioidine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 7-Acetylscorpioidine
Price:
CAS No.: 80405-17-0
Catalog No.: CFN00316
Molecular Formula: C22H33NO7
Molecular Weight: 423.50 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Myosotis scorpioides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 7-Acetylscorpioidine is a natural product from Myosotis scorpioides, its free bases cause ataxia, lethargy, and death in mice, accounting for the previously described "curare-like" action of the crude alkaloid fraction.
In vivo:
Journal of Natural Products, 1982 , 45 (3) :358-362.
Biologically active pyrrolizidine alkaloids from the true forget-me-not, Myosotis scorpioides.[Reference: WebLink]

METHODS AND RESULTS:
Four pyrrolizidine alkaloids have been isolated from the aerial parts of Myosotis scorpioides.
CONCLUSIONS:
They are 7-Acetylscorpioidine (1), scorpioidine (2), symphytine (4), and myoscorpine (5). Their free bases cause ataxia, lethargy, and death in mice, accounting for the previously described "curare-like" action of the crude alkaloid fraction.
7-Acetylscorpioidine Description
Source: The herbs of Myosotis scorpioides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3613 mL 11.8064 mL 23.6128 mL 47.2255 mL 59.0319 mL
5 mM 0.4723 mL 2.3613 mL 4.7226 mL 9.4451 mL 11.8064 mL
10 mM 0.2361 mL 1.1806 mL 2.3613 mL 4.7226 mL 5.9032 mL
50 mM 0.0472 mL 0.2361 mL 0.4723 mL 0.9445 mL 1.1806 mL
100 mM 0.0236 mL 0.1181 mL 0.2361 mL 0.4723 mL 0.5903 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN00306Punctanecine145204-91-7383.48C20H33NO6
CFN00309Sarracine2492-09-3337.41C18H27NO5
CFN00314Neosarracine136173-26-7337.41C18H27NO5
CFN00310Sarracine N-oxide19038-27-8353.41C18H27NO6
CFN00311Racemodine147554-28-7437.53C23H35NO7
CFN00312Neosarranicine136173-27-8337.41C18H27NO5
CFN00313Sarranicine136173-25-6337.41C18H27NO5
CFN00315Scorpioidine80405-18-1381.47C20H31NO6
CFN003167-Acetylscorpioidine80405-17-0423.50C22H33NO7
CFN00317Anadoline N-oxide28513-29-3397.47C20H31NO7
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