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Abiesadine N
Abiesadine N
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Abiesadine N
Price:
CAS No.: 1159913-80-0
Catalog No.: CFN99263
Molecular Formula: C21H30O3
Molecular Weight: 330.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The barks of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Bioorganic & medicinal chemistry, 2010, 18(2):744-754.
Isolation, structure, and bioactivities of abiesadines A–Y, 25 new diterpenes from Abies georgei Orr.[Reference: WebLink]

METHODS AND RESULTS:
Twenty-five new (abiesadines A–Y, 1–25, Abiesadine N) and 29 known (26–54) diterpenes were isolated from the aerial parts of Abies georgei. Abiesadine A (1) is a novel 8,14-seco-abietane, while abiesadine B (2) is a novel 9,10-seco-abietane. The structures of the new compounds were established on the basis of spectroscopic data analysis.
CONCLUSIONS:
Manool (52) showed the strongest effect against LPS-induced NO production in RAW264.7 macrophages with the IC50 value of 11.0 μg/mL. In another anti-inflammatory assay against TNFα-triggered NF-κB activity, (12R,13R)-8,12-epoxy-14-labden-13-ol (54) exhibited the strongest effect (IC50 = 8.7 μg/mL). For antitumor assays, pomiferin A (26) and 8,11,13-abietatriene-7α,18-diol (29) both showed the most significant activity against LOVO cells (IC50 = 9.2 μg/mL). While 7-oxocallitrisic acid (46) exhibited significant cytotoxicity against QGY-7703 tumor cells (IC50 = 10.2 μg/mL).
Abiesadine N Description
Source: The barks of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0257 mL 15.1286 mL 30.2572 mL 60.5144 mL 75.643 mL
5 mM 0.6051 mL 3.0257 mL 6.0514 mL 12.1029 mL 15.1286 mL
10 mM 0.3026 mL 1.5129 mL 3.0257 mL 6.0514 mL 7.5643 mL
50 mM 0.0605 mL 0.3026 mL 0.6051 mL 1.2103 mL 1.5129 mL
100 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.6051 mL 0.7564 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
1-Deoxynojirimycin

Catalog No: CFN99933
CAS No: 19130-96-2
Price: $30/20mg
Lonicerin

Catalog No: CFN95055
CAS No: 25694-72-8
Price: $168/10mg
Ganoderic acid A

Catalog No: CFN92051
CAS No: 81907-62-2
Price: $80/20mg
Sugiol

Catalog No: CFN92187
CAS No: 511-05-7
Price: $ / mg
8-Acetoxypinoresinol

Catalog No: CFN00449
CAS No: 81426-14-4
Price: $ / mg
Daidzein

Catalog No: CFN98774
CAS No: 486-66-8
Price: $30/20mg
Jionoside A1

Catalog No: CFN90809
CAS No: 120444-60-2
Price: $238/5mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
Yatein

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CAS No: 40456-50-6
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Fraxin

Catalog No: CFN99747
CAS No: 524-30-1
Price: $50/20mg
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