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Aeruginolactone
Aeruginolactone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Aeruginolactone
Price:
CAS No.: 1005208-88-7
Catalog No.: CFN92791
Molecular Formula: C15H20O3
Molecular Weight: 248.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The rhizomes of Curcuma rcenyujin Y,H. Chenet C.Ling
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Standard reference
In vitro:
J Pharm Biomed Anal. 2013 Dec;86:161-8.
Characterization of in vivo and in vitro metabolites of furanodiene in rats by high performance liquid chromatography-electrospray ionization mass spectrometry and nuclear magnetic resonance spectra.[Pubmed: 23998967]

METHODS AND RESULTS:
All of these metabolites were phase I metabolites, with three new compounds including 2β-hydroxyl-Aeruginolactone (2), 14-hydroxyl-Aeruginolactone (3), 1β,8β-dihydroxyeudesm-4,7(11)-dien-8α,12-olide (4a), and four known compounds, 1β,10α,4α,5β-diepoxy-8α-hydroxy-glechoman-8α,12-olide (1), 1β,8β-dihydroxyeudesm-4(14),7(11)-dien-8α,12-olide (4b), 1β,8β-dihydroxyeudesm-3,7(11)-dien-8α,12-olide (5) and Aeruginolactone (6). Interestingly, the metabolite 6 was found to be a primary metabolite in urine, bile and feces. All metabolites were found to be both in urine and bile but only few metabolites except the metabolite 6 presented in feces after oral dose of furanodiene to rats. Furthermore, the metabolic pathways of furanodiene were proposed using an in vitro assay by incubation of furanodiene and its metabolites in vivo with rat liver S9 or liver microsomes.
CONCLUSIONS:
Clearly, Aeruginolactone (6) seemed to be a major precursor for other metabolites.
Aeruginolactone Description
Source: The rhizomes of Curcuma rcenyujin Y,H. Chenet C.Ling
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0274 mL 20.1369 mL 40.2739 mL 80.5477 mL 100.6847 mL
5 mM 0.8055 mL 4.0274 mL 8.0548 mL 16.1095 mL 20.1369 mL
10 mM 0.4027 mL 2.0137 mL 4.0274 mL 8.0548 mL 10.0685 mL
50 mM 0.0805 mL 0.4027 mL 0.8055 mL 1.611 mL 2.0137 mL
100 mM 0.0403 mL 0.2014 mL 0.4027 mL 0.8055 mL 1.0068 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $463/5mg
Gancaonin N

Catalog No: CFN95066
CAS No: 129145-52-4
Price: $463/5mg
Betulinic acid

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Price: $40/20mg
Quercetin-3-O-glucuronide

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Myricetin 3-O-galactoside

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Harpagide

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Gymnemic acid I

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Licochalcone A

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Ginkgolic acid C15:1

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