Albaspidin AP | CAS:59092-91-0 | Manufacturer ChemFaces

Albaspidin AP

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Albaspidin AP Description

Source:	The rhizomes of Dryopteris crassirhizoma Nakai
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

《Journal of Tianjin Medical University》 2007-02

Studies on active constituents in rhizome of Dryopteris crassirhizoma[Reference: WebLink]

To study the acylphloroglucinols of the Dryopteris Crassirhizoma Nakai.
METHODS AND RESULTS:
The column chromatography of buffered SiO2 and sephadex were used to isolate those constituents which were identified by chemical knowledge and spectroscopic methods. Nine acylphloroglucinol derivatives were obtained and were identified ,the first three compounds of them:albaspidin AA(Ⅰ),Albaspidin AP(Ⅱ) and albasspidin PP(Ⅲ).
CONCLUSIONS:
The compoundsⅡ,Ⅲ are first obtained as crystals from natural plants and are first found from Dryopteris Crassirhizoma. 1H-NMR and 13C-NMR data of compoundⅡ and compound Ⅲ, and 13C-NMR data of compoundⅠ are first reported. On the basis of variety of 2DNMR experiments, NMR data of the three compound are well assigned.

Product Name	Albaspidin AP
Price:
CAS No.:	59092-91-0
Catalog No.:	CFN90252
Molecular Formula:	C₂₂H₂₆O₈
Molecular Weight:	418.44 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The rhizomes of Dryopteris crassirhizoma Nakai
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Phenols Compound Library Fatty Acid Synthase Inhibitor Library

Description:	Albaspidin-AP, -PP, -PB inhibit Fatty acid synthase (FAS) with IC50 values ranging from 23.1+/-1.4 to 71.7+/-3.9 microM, they could be considered to be a promising class of FAS inhibitors, and FAS is emerging as a potential therapeutic target to treat cancer and obesity.
Targets:	Fatty Acid Synthase

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3898 mL	11.9491 mL	23.8983 mL	47.7966 mL	59.7457 mL
5 mM	0.478 mL	2.3898 mL	4.7797 mL	9.5593 mL	11.9491 mL
10 mM	0.239 mL	1.1949 mL	2.3898 mL	4.7797 mL	5.9746 mL
50 mM	0.0478 mL	0.239 mL	0.478 mL	0.9559 mL	1.1949 mL
100 mM	0.0239 mL	0.1195 mL	0.239 mL	0.478 mL	0.5975 mL

CFN92877	Didemethylpseudoaspidin AA	142382-28-3	376.4	C₁₉H₂₀O₈
CFN90684	Pseudoaspidin	478-28-4	460.5	C₂₅H₃₂O₈
CFN98474	Albaspidin AA	3570-40-9	404.4	C₂₁H₂₄O₈
CFN90252	Albaspidin AP	59092-91-0	418.44	C₂₂H₂₆O₈
CFN99573	Filixic acid ABA	38226-84-5	612.63	C₃₂H₃₆O₁₂
CFN98169	Agrimol B	55576-66-4	682.75	C₃₇H₄₆O₁₂
CFN99519	Dryocrassin ABBA	12777-70-7	820.81	C₄₃H₄₈O₁₆
CFN90561	Gossypol	303-45-7	518.56	C₃₀H₃₀O₈
CFN98529	Acetate gossypol	12542-36-8	578.61	C₃₂H₃₄O₁₀
CFN99601	Sideroxylonal A	145382-68-9	500.5	C₂₆H₂₈O₁₀