Alisol G | CAS:155521-46-3 | Manufacturer ChemFaces

Alisol G

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Size /Price /Stock	10 mM * 1 mL in DMSO / $178 / In-stock
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Description:

Alisol G has hCE2 inhibitory effects.

Targets:

hCE2

In vitro:

Phytochemistry Letters.2015 Sep;13:228–233.

Biotransformation of alisol G by Penicillium janthinellum and the hCE2 inhibitory effects of its metabolites.[Reference: WebLink]

Alisol G, also named 25-anhydroalisol A, is a major triterpene obtained from dried rhizomes of Alisma orientalis. This paper investigated the transformation of Alisol G by fungi and evaluated the hCE2 inhibitory effects of the transformed products.
METHODS AND RESULTS:
By screening whole cells of 10 strains of filamentous fungi, Penicillium janthinellum AS 3.510 exhibited a special capability to transform Alisol G. Four metabolites were obtained, which were determined to be new compounds on the basis of spectroscopic data, including UV, 1D- and 2D-NMR, and HRESIMS. In addition, in an in vitro bioassay, metabolites 1–4 showed significant hCE2 inhibitory activities with IC50 values of 6.81, 16.66, 3.38, and 6.33 μM, respectively.

Alisol G Description

Source:	The tubers of Alisma plantago-aquatica Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Alisol G
Price:	$228 / 5mg
CAS No.:	155521-46-3
Catalog No.:	CFN92548
Molecular Formula:	C₃₀H₄₈O₄
Molecular Weight:	472.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The tubers of Alisma plantago-aquatica Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1155 mL	10.5775 mL	21.1551 mL	42.3101 mL	52.8877 mL
5 mM	0.4231 mL	2.1155 mL	4.231 mL	8.462 mL	10.5775 mL
10 mM	0.2116 mL	1.0578 mL	2.1155 mL	4.231 mL	5.2888 mL
50 mM	0.0423 mL	0.2116 mL	0.4231 mL	0.8462 mL	1.0578 mL
100 mM	0.0212 mL	0.1058 mL	0.2116 mL	0.4231 mL	0.5289 mL

CFN80352	Dehydroalisol B 23-acetate	N/A	512.72	C₃₂H₄₈O₅
CFN92548	Alisol G	155521-46-3	472.7	C₃₀H₄₈O₄
CFN95661	11-Deoxyalisol A	155800-98-9	474.7	C₃₀H₅₀O₄
CFN92542	Alisol A	19885-10-0	490.7	C₃₀H₅₀O₅
CFN92544	Alisol A 23-acetate	19865-75-9	532.75	C₃₂H₅₂O₆
CFN92546	Alisol E 23-acetate	155301-58-9	532.8	C₃₂H₅₂O₆
CFN90198	Alisol A 24-acetate	18674-16-3	532.75	C₃₂H₅₂O₆
CFN92543	25-O-Methylalisol A	155801-00-6	504.7	C₃₁H₅₂O₅
CFN89426	11-Anhydro-16-oxoalisol A	156338-93-1	486.68	C₃₀H₄₆O₅
CFN95662	Alisol P	1005191-19-4	520.7	C₃₀H₄₈O₇