Allitol | CAS:488-44-8 | Manufacturer ChemFaces

Allitol

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Description:

Allitol is useful as a sweetener and the raw material for production of chemical compounds, it can be useful as a substrate for the production of L-form ketoses and aldoses. Allitol may be an important intermediate for the preparation of some medicines against diabetes, cancer, and viral infections, including AIDS.

In vitro:

J Ind Microbiol Biotechnol. 2015 May;42(5):661-9.

Construction of allitol synthesis pathway by multi-enzyme coexpression in Escherichia coli and its application in allitol production.[Pubmed: 25724336]

METHODS AND RESULTS:
An engineered strain for the conversion of D-fructose to Allitol was developed by constructing a multi-enzyme coupling pathway and cofactor recycling system in Escherichia coli. D-Psicose-3-epimerase from Ruminococcus sp. and ribitol dehydrogenase from Klebsiella oxytoca were coexpressed to form the multi-enzyme coupling pathway for Allitol production. The cofactor recycling system was constructed using the formate dehydrogenase gene from Candida methylica for continuous NADH supply. The recombinant strain produced 10.62 g/l Allitol from 100 mM D-fructose. To increase the intracellular concentration of the substrate, the glucose/fructose facilitator gene from Zymomonas mobilis was incorporated into the engineered strain.
CONCLUSIONS:
The results showed that the Allitol yield was enhanced significantly to 16.53 g/l with a conversion rate of 92 %. Through optimizing conversion conditions, Allitol was produced effectively on a large scale by the whole-cell biotransformation system; the yield reached 48.62 g/l when 500 mM D-fructose was used as the substrate.

Allitol Description

Source:	The herbs of Itea yunnanensis Franch.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Allitol
Price:
CAS No.:	488-44-8
Catalog No.:	CFN98777
Molecular Formula:	C₆H₁₄O₆
Molecular Weight:	182.2 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Cryst.
Source:	The herbs of Itea yunnanensis Franch.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Sweeteners Compound Library Precursors Compound Library Miscellaneous Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.4885 mL	27.4424 mL	54.8847 mL	109.7695 mL	137.2119 mL
5 mM	1.0977 mL	5.4885 mL	10.9769 mL	21.9539 mL	27.4424 mL
10 mM	0.5488 mL	2.7442 mL	5.4885 mL	10.9769 mL	13.7212 mL
50 mM	0.1098 mL	0.5488 mL	1.0977 mL	2.1954 mL	2.7442 mL
100 mM	0.0549 mL	0.2744 mL	0.5488 mL	1.0977 mL	1.3721 mL

CFN90045	N-Acetylneuraminic acid	131-48-6	309.27	C₁₁H₁₉NO₉
CFN90046	D-Mannitol	69-65-8	182.17	C₆H₁₄O₆
CFN80242	Dulcitol	608-66-2	182.07	C₆H₁₄O₆
CFN98777	Allitol	488-44-8	182.2	C₆H₁₄O₆
CFN98779	D-arabinitol	488-82-4	152.1	C₅H₁₂O₅
CFN99193	Glucosamine sulfate	29031-19-4	277.25	C₆H₁₅NO₉S
CFN99510	Xylitol	87-99-0	152.15	C₅H₁₂O₅
CFN99620	Erythritol	149-32-6	122.1	C₄H₁₀O₄
CFN91717	D-Mannose	3458-28-4	180.16	C₆H₁₂O₆