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Antiquorin
Antiquorin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Antiquorin
Price:
CAS No.: 125356-08-3
Catalog No.: CFN96856
Molecular Formula: C20H28O3
Molecular Weight: 316.44 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Euphorbia fischeriana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Melbourne (Australia)
  • Amity University (India)
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  • Universite de Lille1 (France)
  • National Cancer Institute (USA)
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  • Centrum Menselijke Erfelijkheid (Belgium)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Antiquorin exhibits moderate cytotoxic activities against the human lung cancer 95-D cell line with the IC50 value of 34.5 uM.
In vitro:
Helvetica Chimica Acta, 2013, 96(6):1182-1187.
Unusual Guaiane Sesquiterpenoids from Artemisia rupestris.[Reference: WebLink]

METHODS AND RESULTS:
Two new guaiane sesquiterpenoids, (1β,5β)-1-hydroxyguaia-4(15),11(13)-dieno-12,5-lactone (1) and 1,5-epoxy-4-hydroxyguai-11(13)-en-12-oic acid (2), together with five known compounds, rupestonic acid (3), strobilactone A (4), Antiquorin (5), isosclerone (6), and 5-hydroxy-2′,3′,4′,7,8-pentamethoxyflavone (7), were isolated from a 95% EtOH extract of Artemisia rupestris. Compounds 1 and 2 are rare examples of guaiane sesquiterpenoids, incorporating a 12,5-lactone group or featuring a 1,5-epoxy ring, respectively. The structures of 1 and 2 were identified by various spectroscopic methods.
CONCLUSIONS:
Compounds 1, 4, and 5 exhibited moderate cytotoxic activities against the human lung cancer 95-D cell line with IC50 values of 11.3, 19.8, and 34.5 μM, respectively.
Antiquorin Description
Source: The roots of Euphorbia fischeriana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1602 mL 15.8008 mL 31.6016 mL 63.2031 mL 79.0039 mL
5 mM 0.632 mL 3.1602 mL 6.3203 mL 12.6406 mL 15.8008 mL
10 mM 0.316 mL 1.5801 mL 3.1602 mL 6.3203 mL 7.9004 mL
50 mM 0.0632 mL 0.316 mL 0.632 mL 1.2641 mL 1.5801 mL
100 mM 0.0316 mL 0.158 mL 0.316 mL 0.632 mL 0.79 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Journal of Natural Medicines, 2010, 8(2):101-103.
Diterpenes and triterpenes from the roots of Euphorbia fischeriana.[Reference: WebLink]
To study the terpenes in the roots of Euphorbia fischeriana.
METHODS AND RESULTS:
The compounds were isolated by silica gel column chromatography,and their structures were identified on the basis of physiochemical and spectral data.Eight diterpenes and four triterpenes were obtained from the ethyl acetate extract,and their structures were elucidated as jolkinolide A(1),jolkinolide B(2),prostratin(3),ent-kaurane-3-oxo-16α,17-diol(4),Antiquorin(5),neriifolene(6),ent-atisane-3β,16α,17-triol(7),kauranoic acid(8),aleuritolic acid(9),24-methyl-enecy- cloartanol(10)and lupenyl acetate(11).
CONCLUSIONS:
Compounds 4-10 were isolated from this plant for the first time.
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trans-Caryophyllene

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