Science | Nature | Cell | View More
Natural Products
Baccatin VI
Baccatin VI
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Baccatin VI
Price:
CAS No.: 57672-79-4
Catalog No.: CFN96925
Molecular Formula: C37H46O14
Molecular Weight: 714.76 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The heartwoods of Taxus baccata L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universiti Malaysia Pahang (Malaysia)
  • VIT University (India)
  • Nanjing University of Chinese M... (China)
  • Rio de Janeiro State University (Brazil)
  • Medical University of South Car... (USA)
  • University of Sao Paulo (Brazil)
  • Utrecht University (Netherlands)
  • Universidad de La Salle (Mexico)
  • Charles Sturt University (Denmark)
  • Institute of Bioorganic Chemist... (Poland)
  • Regional Crop Research Institute (Korea)
  • More...
Package
Featured Products
Isoastragaloside I

Catalog No: CFN90977
CAS No: 84676-88-0
Price: $268/10mg
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Piperine

Catalog No: CFN99919
CAS No: 94-62-2
Price: $30/20mg
Ganoderic acid A

Catalog No: CFN92051
CAS No: 81907-62-2
Price: $80/20mg
Delphinidin-3-O-glucoside chloride

Catalog No: CFN92038
CAS No: 6906-38-3
Price: $238/10mg
24-Methylenecycloartan-3-ol

Catalog No: CFN99496
CAS No: 1449-09-8
Price: $ /
Crocin I

Catalog No: CFN99927
CAS No: 94238-00-3
Price: $100/20mg
Palmatine

Catalog No: CFN98459
CAS No: 3486-67-7
Price: $40/20mg
Asperglaucide

Catalog No: CFN98937
CAS No: 56121-42-7
Price: $238/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Baccatin VI possesses significant antinociceptive activity against p-benzoquinone-induced abdominal contractions.
In vitro:
J Asian Nat Prod Res. 2006 Apr-May;8(3):229-39.
The dynamic variation of several important taxane content in post-harvest Taxus chinensis clippings.[Pubmed: 16864429 ]
The dynamic variations of several important taxanes, taxol, baccatin III (B-III), 1-acety-5,7,10-deacetyl-baccatin I (DAB-I) and Baccatin VI (B-VI), were investigated in post-harvest clippings of Taxus chinensis.
METHODS AND RESULTS:
The clippings were preserved over 20 days at two different temperatures (4 degrees C and room temperature), or by cuttage in the light and in the dark, or promptly dried. The accumulation of taxol in needles of the clippings was found increase in the initial stages of the stored period and then decreased gradually. The maximum accumulation of taxol occurred in the case of cold storing (4 degrees C) at day 3, doubling the data on the day when the biomass was harvested. In contrast, in the cases of cold storage and cuttage the contents of the other three taxanes showed a sharp decrease at the beginning and then an increase from 3 to 6 days, and subsequently a drop until day 20. The similar variation of taxane contents was not found in the needles of immediately dried clippings as well as in the stem samples of clippings.
CONCLUSIONS:
These results indicated that the content variation of taxol and related taxanes of post-harvest clippings was related to the manner of preservation, timing and plant tissue. Moreover, the mechanism of the fluctuation of the taxane contents in post-harvest clippings is discussed, in particular taxol biosynthesis in response to mechanical wounding of harvest.
In vivo:
J Ethnopharmacol. 2003 Dec;89(2-3):265-70.
Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L.[Pubmed: 14611890]

METHODS AND RESULTS:
Four taxoids (taxusin, Baccatin VI, baccatin III and 1beta-hydroxybaccatin I) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropylether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through chromatographic techniques. In vivo anti-inflammatory and antinociceptive activity of these compounds were investigated.
CONCLUSIONS:
All the compounds were shown to possess significant antinociceptive activity against p-benzoquinone-induced abdominal contractions, while only lignan derivatives significantly inhibited carrageenan-induced hind paw edema in mice.
Baccatin VI Description
Source: The heartwoods of Taxus baccata L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
12beta-Acetoxy-7beta-hydroxy-3,11,...

Catalog No: CFN95515
CAS No: 1245946-62-6
Price: $318/5mg
5-O-Coumaroylquinic acid

Catalog No: CFN95507
CAS No: 32451-86-8
Price: $318/5mg
Ganoweberianic acid E

Catalog No: CFN95504
CAS No: 1309931-90-5
Price: $413/5mg
Methyl 2-hydroxy-3,4-dimethoxybenz...

Catalog No: CFN95383
CAS No: 6395-23-9
Price: $268/5mg
Arvenin III

Catalog No: CFN95327
CAS No: 65597-45-7
Price: $318/5mg
Selina-4(15),7(11)-dien-8-one

Catalog No: CFN95078
CAS No: 54707-47-0
Price: $288/10mg
Oxytroflavoside E

Catalog No: CFN95464
CAS No: 1391144-84-5
Price: $318/5mg
Kihadanin D

Catalog No: CFN95482
CAS No: 2770024-83-2
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3991 mL 6.9954 mL 13.9907 mL 27.9814 mL 34.9768 mL
5 mM 0.2798 mL 1.3991 mL 2.7981 mL 5.5963 mL 6.9954 mL
10 mM 0.1399 mL 0.6995 mL 1.3991 mL 2.7981 mL 3.4977 mL
50 mM 0.028 mL 0.1399 mL 0.2798 mL 0.5596 mL 0.6995 mL
100 mM 0.014 mL 0.07 mL 0.1399 mL 0.2798 mL 0.3498 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Isoastragaloside I

Catalog No: CFN90977
CAS No: 84676-88-0
Price: $268/10mg
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Piperine

Catalog No: CFN99919
CAS No: 94-62-2
Price: $30/20mg
Ganoderic acid A

Catalog No: CFN92051
CAS No: 81907-62-2
Price: $80/20mg
Delphinidin-3-O-glucoside chloride

Catalog No: CFN92038
CAS No: 6906-38-3
Price: $238/10mg
24-Methylenecycloartan-3-ol

Catalog No: CFN99496
CAS No: 1449-09-8
Price: $ /
Crocin I

Catalog No: CFN99927
CAS No: 94238-00-3
Price: $100/20mg
Palmatine

Catalog No: CFN98459
CAS No: 3486-67-7
Price: $40/20mg
Asperglaucide

Catalog No: CFN98937
CAS No: 56121-42-7
Price: $238/5mg
Tags: buy Baccatin VI | Baccatin VI supplier | purchase Baccatin VI | Baccatin VI cost | Baccatin VI manufacturer | order Baccatin VI | Baccatin VI distributor