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Blepharotriol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Blepharotriol
Price:
CAS No.: 849590-42-7
Catalog No.: CFN91916
Molecular Formula: C29H38O6
Molecular Weight: 482.61 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Tripterygium wilfordii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Blepharotriol may have antimicrobial and cytotoxic activities.
Targets: Antifection
Blepharotriol Description
Source: The herbs of Tripterygium wilfordii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0721 mL 10.3603 mL 20.7207 mL 41.4413 mL 51.8017 mL
5 mM 0.4144 mL 2.0721 mL 4.1441 mL 8.2883 mL 10.3603 mL
10 mM 0.2072 mL 1.036 mL 2.0721 mL 4.1441 mL 5.1802 mL
50 mM 0.0414 mL 0.2072 mL 0.4144 mL 0.8288 mL 1.036 mL
100 mM 0.0207 mL 0.1036 mL 0.2072 mL 0.4144 mL 0.518 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 2005, 61(9):2513-2519.
New phenolic triterpenes from Maytenus blepharodes. Semisynthesis of 6-deoxoblepharodol from pristimerin[Reference: WebLink]

METHODS AND RESULTS:
Four new phenolic triterpenes with a 24-nor-D:A-friedoleane skeleton, isoblepharodol, 7-oxoblepharodol, Blepharotriol and 6-deoxoblepharodol, were isolated from Maytenus blepharodes. Their structures were elucidated on the basis of spectroscopic analysis, including homo and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC, and HMBC). The semisynthesis of 6-deoxoblepharodol and its epimer at C-8 was achieved by catalytic reduction of pristimerin, a quinone-methide triterpene present in the plant. The biosynthetic formation of the phenolic triterpenes isolated from this species is also discussed.
CONCLUSIONS:
The compounds were assayed for antimicrobial and cytotoxic activities.
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Epigoitrin

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