Science | Nature | Cell | View More
Natural Products
Chilenine
Chilenine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Chilenine
Price:
CAS No.: 71700-15-7
Catalog No.: CFN89525
Molecular Formula: C20H17NO7
Molecular Weight: 383.35 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Hydrastis canadensis L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Vigo (Spain)
  • Almansora University (Egypt)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Aveiro University (Portugal)
  • Kyung Hee University (Korea)
  • Universidade Federal de Goias (... (Brazil)
  • Universit?t Basel (Switzerland)
  • Weizmann Institute of Science (Israel)
  • MTT Agrifood Research Finland (Finland)
  • University of Dicle (Turkey)
  • Georgia Institute of Technology (USA)
  • More...
Package
Featured Products
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Isovitexin-2''-O-rhamnoside (2''-O...

Catalog No: CFN95314
CAS No: 72036-50-1
Price: $368/10mg
Scoparone

Catalog No: CFN99314
CAS No: 120-08-1
Price: $30/20mg
Momordicine II

Catalog No: CFN95167
CAS No: 91590-75-9
Price: $318/10mg
Hirsuteine

Catalog No: CFN90615
CAS No: 35467-43-7
Price: $268/5mg
Eurycomanone

Catalog No: CFN92008
CAS No: 84633-29-4
Price: $268/20mg
3-O-beta-D-Glucopyranosylplatycodi...

Catalog No: CFN90950
CAS No: 38337-25-6
Price: $268/5mg
2'-Acetylacteoside

Catalog No: CFN92452
CAS No: 94492-24-7
Price: $188/20mg
2''-O-Rhamnosylicariside II

Catalog No: CFN92551
CAS No: 135293-13-9
Price: $288/10mg
Artesunate

Catalog No: CFN90313
CAS No: 88495-63-0
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Chilenine is a natural product from Hydrastis canadensis L.
In vitro:
Phytochem Lett. 2017 Jun;20:54-60.
Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis).[Pubmed: 28736584]
The study presented herein constitutes an extensive investigation of constituents in Hydrastis canadensis L. (Ranunculaceae) leaves.
METHODS AND RESULTS:
It describes the isolation and identification of two previously unknown compounds, 3,4-dimethoxy-2-(methoxycarbonyl)benzoic acid (1) and 3,5,3'-trihydroxy-7,4'-dimethoxy-6,8-C-dimethyl-flavone (2), along with the known compounds (±)-Chilenine (3), (2R)-5,4'-dihydroxy-6-C-methyl-7-methoxy-flavanone (4), 5,4'-dihydroxy-6,8-di-C-methyl-7-methoxy-flavanone (5), noroxyhydrastinine (6), oxyhydrastinine (7) and 4',5'-dimethoxy-4-methyl-3'-oxo-(1,2,5,6-tetrahydro-4H-1,3-dioxolo-[4',5':4,5]-benzo[1,2-e]-1,2-oxazocin)-2-spiro-1'-phtalan (8). Compounds 3-8 have been reported from other sources, but this is the first report of their presence in H. canadensis extracts.
CONCLUSIONS:
A mass spectrometry based assay was employed to demonstrate bacterial efflux pump inhibitory activity against Staphylococcus aureus for 2, with an IC50 value of 180 ± 6 μM. This activity in addition to that of other bioactive compounds such as flavonoids and alkaloids, may explain the purported efficacy of H. canadensis for treatment of bacterial infections. Finally, this report includes high mass accuracy fragmentation spectra for all compounds investigated herein which were uploaded into the Global Natural Products Social molecular networking library and can be used to facilitate their future identification in H. canadensis or other botanicals.
Chilenine Description
Source: The leaves of Hydrastis canadensis L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Neochlorogenic acid methyl ester

Catalog No: CFN95190
CAS No: 123410-65-1
Price: $198/5mg
Ganoderiol D

Catalog No: CFN95568
CAS No: 114567-45-2
Price: $413/5mg
Ginsenoside F5

Catalog No: CFN95034
CAS No: 189513-26-6
Price: $298/20mg
Parvisoflavanone

Catalog No: CFN95077
CAS No: 49776-79-6
Price: $413/5mg
4-O-Caffeoyl-3-O-syringoylquinic a...

Catalog No: CFN95430
CAS No: 1207645-17-7
Price: $413/5mg
3-Hydroxymollugin

Catalog No: CFN95424
CAS No: 154706-45-3
Price: $368/5mg
Gynosaponin TN2

Catalog No: CFN95331
CAS No: 77658-95-8
Price: $318/5mg
Maingayone B

Catalog No: CFN95483
CAS No: 1071223-57-8
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6086 mL 13.0429 mL 26.0858 mL 52.1716 mL 65.2146 mL
5 mM 0.5217 mL 2.6086 mL 5.2172 mL 10.4343 mL 13.0429 mL
10 mM 0.2609 mL 1.3043 mL 2.6086 mL 5.2172 mL 6.5215 mL
50 mM 0.0522 mL 0.2609 mL 0.5217 mL 1.0434 mL 1.3043 mL
100 mM 0.0261 mL 0.1304 mL 0.2609 mL 0.5217 mL 0.6521 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Isovitexin-2''-O-rhamnoside (2''-O...

Catalog No: CFN95314
CAS No: 72036-50-1
Price: $368/10mg
Scoparone

Catalog No: CFN99314
CAS No: 120-08-1
Price: $30/20mg
Momordicine II

Catalog No: CFN95167
CAS No: 91590-75-9
Price: $318/10mg
Hirsuteine

Catalog No: CFN90615
CAS No: 35467-43-7
Price: $268/5mg
Eurycomanone

Catalog No: CFN92008
CAS No: 84633-29-4
Price: $268/20mg
3-O-beta-D-Glucopyranosylplatycodi...

Catalog No: CFN90950
CAS No: 38337-25-6
Price: $268/5mg
2'-Acetylacteoside

Catalog No: CFN92452
CAS No: 94492-24-7
Price: $188/20mg
2''-O-Rhamnosylicariside II

Catalog No: CFN92551
CAS No: 135293-13-9
Price: $288/10mg
Artesunate

Catalog No: CFN90313
CAS No: 88495-63-0
Price: $30/20mg
Tags: buy Chilenine | Chilenine supplier | purchase Chilenine | Chilenine cost | Chilenine manufacturer | order Chilenine | Chilenine distributor