Coclauril | CAS:127350-68-9 | Manufacturer ChemFaces

Coclauril

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Coclauril shows anti-Hepatitis B virus (HBV) activities, with EC50 values of 7.6 ± 0.5 ug/mL.

Targets:

HBV

In vitro:

Molecules. 2015 Aug 12;20(8):14565-75.

Four New Cyclohexylideneacetonitrile Derivatives from the Hypocotyl of Mangrove (Bruguiera gymnorrhiza).[Pubmed: 26274945 ]

METHODS AND RESULTS:
Four new cyclohexylideneacetonitrile derivatives 1-4, named menisdaurins B-E, as well as three known cyclohexylideneacetonitrile derivatives--menisdaurin (5), Coclauril (6), and menisdaurilide (7)--were isolated from the hypocotyl of a mangrove (Bruguiera gymnorrhiza). The structures of the isolates were elucidated on the basis of extensive spectroscopic analysis.
CONCLUSIONS:
Compounds 1-7 showed anti-Hepatitis B virus (HBV) activities, with EC50 values ranging from 5.1 ± 0.2 μg/mL to 87.7 ± 5.8 μg/mL.

Coclauril Description

Source:	The herbs of Cocculus laurifolius
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Coclauril
Price:
CAS No.:	127350-68-9
Catalog No.:	CFN99383
Molecular Formula:	C₈H₉NO₂
Molecular Weight:	151.2 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Oil
Source:	The herbs of Cocculus laurifolius
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Alkaloids Compound Library HBV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.6138 mL	33.0688 mL	66.1376 mL	132.2751 mL	165.3439 mL
5 mM	1.3228 mL	6.6138 mL	13.2275 mL	26.455 mL	33.0688 mL
10 mM	0.6614 mL	3.3069 mL	6.6138 mL	13.2275 mL	16.5344 mL
50 mM	0.1323 mL	0.6614 mL	1.3228 mL	2.6455 mL	3.3069 mL
100 mM	0.0661 mL	0.3307 mL	0.6614 mL	1.3228 mL	1.6534 mL

CFN99383	Coclauril	127350-68-9	151.2	C₈H₉NO₂
CFN90410	Menisdaurin	67765-58-6	313.30	C₁₄H₁₉NO₇
CFN97404	5-Epilithospermoside	84799-31-5	329.3	C₁₄H₁₉NO₈
CFN99780	Lithospermoside	63492-69-3	329.30	C₁₄H₁₉NO₈
CFN98974	(2,4-Dihydroxyphenyl)acetonitrile	57576-34-8	149.2	C₈H₇NO₂
CFN99664	Ehretioside B	156368-84-2	311.3	C₁₄H₁₇NO₇
CFN97079	p-Vinylphenyl O-beta-D-glucopyranoside	62470-46-6	282.3	C₁₄H₁₈O₆
CFN99216	p-Vinylphenyl O-[beta-D-apiofuranosyl-(1-6)]-beta-D-glucopyranoside	112047-91-3	414.4	C₁₉H₂₆O₁₀
CFN97473	Ptelatoside B	90852-99-6	428.4	C₂₀H₂₈O₁₀