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Coleonol B
Coleonol B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Coleonol B
Price:
CAS No.: 64657-21-2
Catalog No.: CFN97108
Molecular Formula: C22H34O7
Molecular Weight: 410.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Coleus forskohlii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: Coleonol B a natural product from Coleus forskohlii.
Coleonol B Description
Source: The herbs of Coleus forskohlii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4361 mL 12.1803 mL 24.3605 mL 48.7211 mL 60.9013 mL
5 mM 0.4872 mL 2.4361 mL 4.8721 mL 9.7442 mL 12.1803 mL
10 mM 0.2436 mL 1.218 mL 2.4361 mL 4.8721 mL 6.0901 mL
50 mM 0.0487 mL 0.2436 mL 0.4872 mL 0.9744 mL 1.218 mL
100 mM 0.0244 mL 0.1218 mL 0.2436 mL 0.4872 mL 0.609 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zeitschrift für Kristallographie - Crystalline Materials, 1991, 194(1-4):229-234.
Molecular and crystal structure of Coleonol-B, C22H34O7*[Reference: WebLink]
Coleonol B a diterpenoid isolated from the roots of the Indian plant Coleus forskohlii crystallizes in the orthorhombic system, space group P2(1)2(1)2(1) with a = 29.085(5), b = 11.603(2), c = 6.341(1) angstrom and four molecules in the unit cell. As in Coleonol, the substituents at the 6- and 7-positions are in the beta-configuration. 2133 reflections were used, 398 parameters were refined. Final R-values were R(w) = 0.057 and R = 0.045.
CFN9782913-Epijhanol133005-15-9306.49C20H34O2
CFN90186Forskolin66575-29-9410.50C22H34O7
CFN97108Coleonol B64657-21-2410.5 C22H34O7
CFN98709Forskolin G473981-11-2436.6 C24H36O7
CFN97298Forskolin J81873-08-7452.5 C24H36O8
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