Cynatratoside A | CAS:97399-96-7 | Manufacturer ChemFaces

Cynatratoside A

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Description:

Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis.

Targets:

Antifection

In vitro:

Parasitology. 2017 Feb;144(2):179-185.

Activity of two extracts of Cynanchum paniculatum against Ichthyophthirius multifiliis theronts and tomonts.[Pubmed: 27928976]

METHODS AND RESULTS:
The present study aims to evaluate the antiparasitic activity of active components from Cynanchum paniculatum against Ichthyophthirius multifiliis. The antiparasitic activities of two bioassay-guided fractionationated compounds from C. paniculatum identified as Cynatratoside A and Cynanversicoside C, by comparing spectral data (NMR and ESI-MS) with literature values, were evaluated by in vitro assay. These showed that both could kill theronts of I. multifiliis at a concentration of 10·0 mg L-1, with the median effective concentration (EC50) values of 4·6 mg L-1 and 5·2 mg L-1 for Cynatratoside A and Cynanversicoside C, respectively. Encysted tomonts were killed at concentrations of 8·0 mg L-1 with both compounds. In vivo experiments demonstrated that fish treated with both compounds at 15·0 mg L-1 carried significantly fewer parasites than controls (P < 0·05).
CONCLUSIONS:
There were no mortalities among treated fish group compared with 75% mortality of untreated fish. Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against I. multifiliis.

Cynatratoside A Description

Source:	The roots of Cynanchum paniculatum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Cynatratoside A
Price:
CAS No.:	97399-96-7
Catalog No.:	CFN96784
Molecular Formula:	C₂₈H₄₀O₈
Molecular Weight:	504.62 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The roots of Cynanchum paniculatum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiparasitic Compound Library Steroids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9817 mL	9.9084 mL	19.8169 mL	39.6338 mL	49.5422 mL
5 mM	0.3963 mL	1.9817 mL	3.9634 mL	7.9268 mL	9.9084 mL
10 mM	0.1982 mL	0.9908 mL	1.9817 mL	3.9634 mL	4.9542 mL
50 mM	0.0396 mL	0.1982 mL	0.3963 mL	0.7927 mL	0.9908 mL
100 mM	0.0198 mL	0.0991 mL	0.1982 mL	0.3963 mL	0.4954 mL

CFN96964	Otophylloside B	106758-54-7	923.13	C₄₉H₇₈O₁₆
CFN80437	Qingyangshengenin A	106644-33-1	933.09	C₄₉H₇₂O₁₇
CFN96087	Dregeoside A11	89020-11-1	1101.3	C₅₅H₈₈O₂₂
CFN89225	Otophylloside B 4'''-O-alpha-L-cymaropyranoside	171422-82-5	1067.31	C₅₆H₉₀O₁₉
CFN89237	Otophylloside B 4'''-O-beta-D-cymaropyranoside	171422-85-8	1067.31	C₅₆H₉₀O₁₉
CFN89226	Otophylloside B 4'''-O-beta-D-oleandropyranoside	168001-54-5	1067.31	C₅₆H₉₀O₁₉
CFN89036	Otophylloside O	1326583-08-7	1077.25	C₅₆H₈₄O₂₀
CFN96784	Cynatratoside A	97399-96-7	504.62	C₂₈H₄₀O₈
CFN96787	Glaucogenin C mono-D-thevetoside	849201-84-9	520.61	C₂₈H₄₀O₉
CFN95299	Glaucoside A	81474-91-1	520.2	C₂₈H₄₀O₉