2-O-cinnamoyl-beta-D-glucose | CAS:N/A

2-O-cinnamoyl-beta-D-glucose

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Size /Price /Stock	10 mM * 1 mL in DMSO / $185.3 / In-stock
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2-O-cinnamoyl-beta-D-glucose Description

Source:	The rhizomes of Rheum palmatum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

Planta Med. 2000 Dec;66(8):753-6.

Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis.[Pubmed: 11199136 ]

METHODS AND RESULTS:
Galloyl glucoses and galloyl proanthocyanidins obtained from rhubarb (Rhei Rhizoma, Rheum palmatum L., Polygonaceae); e.g. 1,2,6-tri-O-galloyl-beta-D-glucose (IC50 = 0.63 microM), 1,6-di-O-galloyl-2-O-cinnamoyl-beta-D-glucose (IC50 = 0.58 microM), procyanidin B-2 3,3'-di-O-gallate (IC50 = 0.54 microM), and procyanidin B-5 3,3'-di-O-gallate (IC50 = 0.55 microM), were found to be potent inhibitors of rat squalene epoxidase (SE). The inhibition at submicromolar level was far more potent than that of chemically synthesized substrate analogs.
CONCLUSIONS:
It was demonstrated for the first time that the cholesterol-lowering effect of rhubarb may be attributed to the potent inhibition activities of SE, a rate-limiting enzyme of cholesterol biogenesis.

Product Name	2-O-cinnamoyl-beta-D-glucose
Price:	$318 / 20mg
CAS No.:	N/A
Catalog No.:	CFN95111
Molecular Formula:	C₁₅H₁₈O₇
Molecular Weight:	310.3 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The rhizomes of Rheum palmatum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.2227 mL	16.1134 mL	32.2269 mL	64.4538 mL	80.5672 mL
5 mM	0.6445 mL	3.2227 mL	6.4454 mL	12.8908 mL	16.1134 mL
10 mM	0.3223 mL	1.6113 mL	3.2227 mL	6.4454 mL	8.0567 mL
50 mM	0.0645 mL	0.3223 mL	0.6445 mL	1.2891 mL	1.6113 mL
100 mM	0.0322 mL	0.1611 mL	0.3223 mL	0.6445 mL	0.8057 mL

CFN99715	Forsythoside B	81525-13-5	756.70	C₃₄H₄₄O₁₉
CFN99714	Poliumoside	94079-81-9	770.73	C₃₅H₄₆O₁₉
CFN90882	Brandioside	133393-81-4	812.8	C₃₇H₄₈O₂₀
CFN98105	Echinacoside	82854-37-3	786.72	C₃₅H₄₆O₂₀
CFN95035	2'-Rhamnoechinacoside	1422390-59-7	932.9	C₄₁H₅₆O₂₄
CFN93410	Purpureaside C	108648-07-3	786.7	C₃₅H₄₆O₂₀
CFN90809	Jionoside A1	120444-60-2	800.8	C₃₆H₄₈O₂₀
CFN90729	Jionoside B1	120406-37-3	814.78	C₃₇H₅₀O₂₀
CFN90669	Tubuloside A	112516-05-9	828.76	C₃₇H₄₈O₂₁
CFN91712	Tubuloside B	112516-04-8	666.6	C₃₁H₃₈O₁₆