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Dicrotaline
Dicrotaline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Dicrotaline
Price:
CAS No.: 480-87-5
Catalog No.: CFN00367
Molecular Formula: C14H19NO5
Molecular Weight: 281.31 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Crotalaria pallida Ait.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Dicrotaline Description
Source: The herbs of Crotalaria pallida Ait.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5548 mL 17.774 mL 35.548 mL 71.0959 mL 88.8699 mL
5 mM 0.711 mL 3.5548 mL 7.1096 mL 14.2192 mL 17.774 mL
10 mM 0.3555 mL 1.7774 mL 3.5548 mL 7.1096 mL 8.887 mL
50 mM 0.0711 mL 0.3555 mL 0.711 mL 1.4219 mL 1.7774 mL
100 mM 0.0355 mL 0.1777 mL 0.3555 mL 0.711 mL 0.8887 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of the Chemical Society Chemical Communications, 1991, 1(1):19-21.
Biosynthesis of the 3-hydroxy-3-methylglutarate portion of the pyrrolizidine alkaloid dicrotaline.[Reference: WebLink]

METHODS AND RESULTS:
The necic acid portion of Dicrotaline 1, 3-hydroxy-3-methylglutaric acid 3, is not formed specifically from acetate, mevalonate or 3-hydroxy-3-methylglutarate, but label from C-5 of isoleucine 4 is incorporated specifically into the methyl group of this necic acid.
CFN00357Crobarbatine49679-23-4295.33C15H21NO5
CFN00358Crocandine72855-83-5311.38C16H25NO5
CFN00359Isocrocandine72903-70-9311.30C16H25NO5
CFN00361Cropodine83601-85-8327.37C16H25NO6
CFN00365Crotaleschenine120154-95-2309.36C16H23NO5
CFN00367Dicrotaline480-87-5281.31C14H19NO5
CFN00370Fulvine6029-87-4309.36C16H23NO5
CFN00411Retusine480-86-4311.38C16H25NO5
CFN98135Crotaline315-22-0325.36C16H23NO6
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