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Esculentoside E
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Product Name Esculentoside E
Price:
CAS No.: 65649-36-7
Catalog No.: CFN98166
Molecular Formula: C35H54O11
Molecular Weight: 650.80 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Phytolacca acinosa Roxb
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Esculentoside E Description
Source: The roots of Phytolacca acinosa Roxb
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5366 mL 7.6829 mL 15.3657 mL 30.7314 mL 38.4143 mL
5 mM 0.3073 mL 1.5366 mL 3.0731 mL 6.1463 mL 7.6829 mL
10 mM 0.1537 mL 0.7683 mL 1.5366 mL 3.0731 mL 3.8414 mL
50 mM 0.0307 mL 0.1537 mL 0.3073 mL 0.6146 mL 0.7683 mL
100 mM 0.0154 mL 0.0768 mL 0.1537 mL 0.3073 mL 0.3841 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Acta pharmaceutica sinica, 1984.
STUDIES ON THE ACTIVE PRINCIPLES OF THE CHINESE DRUG "SHANG LU" (PHYTOLACCA ESCULENTA VAN HO UTTE)Ⅱ. THE ISOLATION AND STRUCTURE OF ESCULENTOSIDE E AND F.[Reference: WebLink]
In a previous paper we reported the isolation of esculentoside A, B, C and D from Phytolacca eseulenta Van Houtte.In pharmacological experiments the total saponins and esculentoside A exerted considerable enhancement of phagocytic function of leucocytes and promoted DNA synthesis in mice. .
METHODS AND RESULTS:
In further search for active principles, four kinds of crystals (Ⅰ), (Ⅱ), (Ⅲ) and (Ⅳ) were isolated from the 0.01 M pH 7.3 phosphate buffer extract of the plant by silica gel column chromatography. On the basis of chemical properties and spectral data (NMR, ~(13)CNMR, UV, IR, Ms spectra), crystal (Ⅰ) was shown to be 2-hydroxyl esculentic acid, i.e. jaligonic acid which has been considered to have good antiinflammatory action; crystal (Ⅱ) was found to be 3-O-β-D-xylopyranosyl-2-hydroxylesculentic acid and was named as esculentosid E which is identical to phytolaccoside G from Phytolacca americana. Crystal (Ⅲ) is 3-O(β-D-glucopyranosyl-β-D-xylopyranosyl)_(1→4)-2-hydroxyl esculentic acid named as esculentoside F.
CONCLUSIONS:
Esculentoside E was first obtained from this plant and esculentoside F so far has not been reported in literature. Because of the scanty sample of crystal (Ⅳ), its structure is still under investigation.
Sennoside B

Catalog No: CFN99904
CAS No: 128-57-4
Price: $40/20mg
Dehydroabietic acid

Catalog No: CFN99822
CAS No: 1740-19-8
Price: $40/20mg
Zerumbone

Catalog No: CFN91066
CAS No: 471-05-6
Price: $70/20mg
Quassin

Catalog No: CFN97246
CAS No: 76-78-8
Price: $338/5mg
Scutellarein

Catalog No: CFN98557
CAS No: 529-53-3
Price: $60/20mg
5'-Guanylic acid

Catalog No: CFN91721
CAS No: 85-32-5
Price: $30/20mg
Arctiin

Catalog No: CFN99991
CAS No: 20362-31-6
Price: $30/20mg
Irigenin

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CAS No: 548-76-5
Price: $118/20mg
Isoliensinine

Catalog No: CFN99574
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Price: $80/20mg
Polyphyllin D

Catalog No: CFN90255
CAS No: 50773-41-6
Price: $118/20mg
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