Science | Nature | Cell | View More
Natural Products
Ethyl cinnamate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ethyl cinnamate
Price: $30 / 20mg
CAS No.: 103-36-6
Catalog No.: CFN98199
Molecular Formula: C11H12O2
Molecular Weight: 176.21 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Oil
Source: The barks of Cinnamomum cassia Presl
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Illinois (USA)
  • Stanford University (USA)
  • University of Oslo (Norway)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Uniwersytet Jagielloński w Kra... (Poland)
  • Institute of Tropical Disease U... (Indonesia)
  • Utrecht University (Netherlands)
  • University of Canterbury (New Zealand)
  • University of Mysore (India)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Colorado State University (USA)
  • More...
Package
Featured Products
L-Aspartic acid

Catalog No: CFN70148
CAS No: 56-84-8
Price: $30/20mg
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
1,2,3,4,6-O-Pentagalloylglucose

Catalog No: CFN90192
CAS No: 14937-32-7
Price: $80/20mg
Lycopsamine

Catalog No: CFN00287
CAS No: 10285-07-1
Price: $ /
Lasiocarpine

Catalog No: CFN00289
CAS No: 303-34-4
Price: $ /
Isoalantolactone

Catalog No: CFN98107
CAS No: 470-17-7
Price: $40/20mg
Notopterol

Catalog No: CFN98563
CAS No: 88206-46-6
Price: $80/20mg
Isoliensinine

Catalog No: CFN99574
CAS No: 6817-41-0
Price: $80/20mg
Paeonol

Catalog No: CFN98926
CAS No: 552-41-0
Price: $30/20mg
Ferruginol

Catalog No: CFN92178
CAS No: 514-62-5
Price: $ / mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ethyl cinnamate has antifungal, and vasorelaxant effects, it can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 +/- 0.05 mM and 0.38 +/- 0.04 mM. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction.Ethyl cinnamate has acute inhibition to the maximum quantum yield and the potential activity of photosystem II of Chlorella pyrenoidosa.
Targets: ROS | NO | Calcium Channel | Potassium Channel | Antifection
In vitro:
ScientificWorldJournal. 2015;2015:107823.
Toxic Effects of Ethyl Cinnamate on the Photosynthesis and Physiological Characteristics of Chlorella vulgaris Based on Chlorophyll Fluorescence and Flow Cytometry Analysis.[Pubmed: 26101784]
The toxic effects of Ethyl cinnamate on the photosynthetic and physiological characteristics of Chlorella vulgaris were studied based on chlorophyll fluorescence and flow cytometry analysis.
METHODS AND RESULTS:
Parameters, including biomass, F(v)/F(m) (maximal photochemical efficiency of PSII), Ф(PSII) (actual photochemical efficiency of PSII in the light), FDA, and PI staining fluorescence, were measured. The results showed the following: (1) The inhibition on biomass increased as the exposure concentration increased. 1 mg/L Ethyl cinnamate was sufficient to reduce the total biomass of C. vulgaris. The 48-h and 72-h EC50 values were 2.07 mg/L (1.94-2.20) and 1.89 mg/L (1.82-1.97). (2) After 24 h of exposure to 2-4 mg/L Ethyl cinnamate, the photosynthesis of C. vulgaris almost ceased, manifesting in Ф(PSII) being close to zero. After 72 h of exposure to 4 mg/L Ethyl cinnamate, the Fv /Fm of C. vulgaris dropped to zero. (3) Ethyl cinnamate also affected the cellular physiology of C. vulgaris, but these effects resulted in the inhibition of cell yield rather than cell death.
CONCLUSIONS:
Exposure to Ethyl cinnamate resulted in decreased esterase activities in C. vulgaris, increased average cell size, and altered intensities of chlorophyll a fluorescence. Overall, esterase activity was the most sensitive variable.
Huan Jing Ke Xue. 2013 Jan;34(1):156-62.
Effects of allelochemicals ethyl cinnamate on the growth and physiological characteristics of Chlorella pyrenoidosa.[Pubmed: 23487932]
The effects of Ethyl cinnamate on the growth and physiological characteristics of Chlorella pyrenoidosa were studied. The allelopathic mechanisms were explored, from views of chlorophyll a content, antioxidant enzyme activities, reactive oxygen species (ROS) level, malondialdehyde (MDA) content and photosynthetic activity.
METHODS AND RESULTS:
The results revealed that Ethyl cinnamate had acute inhibitory effects on the growth of Chlorella pyrenoidosa, and the inhibited degree tended to increase with increased concentrations. The effective concentration causing a 50% inhibition at 96 h was 5.45 mg c L(-1). Ethyl cinnamate induced the decrease of chlorophyll a, the over-accumulation of ROS and the increase of MDA. Therefore, it suggested that Ethyl cinnamate could lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. And for scavenging ROS, the algae cells were protected from oxidative damages through increasing the activity of antioxidant enzymes.
CONCLUSIONS:
The results demonstrated Ethyl cinnamate had acute inhibition to the maximum quantum yield and the potential activity of photosystem II of Chlorella pyrenoidosa, however, the photosynthetic activity could recover to some extent through self-regulation after some time.
Fitoterapia. 2000 Sep;71(5):567-9.
Antifungal properties of Ocimum gratissimum essential oil (ethyl cinnamate chemotype).[Pubmed: 11449510]
Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes.
CONCLUSIONS:
An Indian chemotype, with a high level of Ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties.
In vivo:
Food Chem Toxicol. 2007;45 Suppl 1:S90-4.
Fragrance material review on ethyl cinnamate.[Pubmed: 18037216]
A toxicologic and dermatologic review of Ethyl cinnamate when used as a fragrance ingredient is presented.
Ethyl cinnamate Description
Source: The barks of Cinnamomum cassia Presl
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Methyl lucidenate G

Catalog No: CFN95058
CAS No: 102607-20-5
Price: $413/5mg
4-O-Coumaroylquinic acid

Catalog No: CFN95508
CAS No: 53539-37-0
Price: $318/5mg
6-Methoxyfraxinellone

Catalog No: CFN95485
CAS No: N/A
Price: $318/10mg
Magnaldehyde B

Catalog No: CFN95075
CAS No: 92829-72-6
Price: $318/5mg
Arisanschinin E

Catalog No: CFN95221
CAS No: 1333378-33-8
Price: $ / mg
Lathyranoic acid A

Catalog No: CFN95325
CAS No: 850560-44-0
Price: $318/5mg
Aegineoside

Catalog No: CFN95270
CAS No: 752209-48-6
Price: $413/5mg
Perlolyrine

Catalog No: CFN95291
CAS No: 29700-20-7
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.675 mL 28.3752 mL 56.7505 mL 113.5009 mL 141.8762 mL
5 mM 1.135 mL 5.675 mL 11.3501 mL 22.7002 mL 28.3752 mL
10 mM 0.5675 mL 2.8375 mL 5.675 mL 11.3501 mL 14.1876 mL
50 mM 0.1135 mL 0.5675 mL 1.135 mL 2.27 mL 2.8375 mL
100 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.135 mL 1.4188 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
Planta Med. 2002 Jul;68(7):655-7.
Vasorelaxant effects of ethyl cinnamate isolated from Kaempferia galanga on smooth muscles of the rat aorta.[Pubmed: 12143006]
From the rhizomes of Kaempferia galanga, Ethyl cinnamate (EC) was isolated and its vasorelaxant effect was examined on the rat aorta.
METHODS AND RESULTS:
EC inhibited the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 +/- 0.05 mM and 0.38 +/- 0.04 mM. The relaxant effect against PE-induced contractions was greater in the presence of endothelium. Pre-treatment of the aorta with methylene blue and indomethacin significantly reduced the relaxant effect. These results suggest that the inhibitory effects of EC may involve inhibition of Ca2+ influx into vascular cells and release of nitric oxide (NO) and prostacyclin from the endothelial cells.
CONCLUSIONS:
Thus, the vasorelaxant effect of EC mediated through multiple pathways may explain the traditional use of the parent plant in treating hypertension.
L-Aspartic acid

Catalog No: CFN70148
CAS No: 56-84-8
Price: $30/20mg
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
1,2,3,4,6-O-Pentagalloylglucose

Catalog No: CFN90192
CAS No: 14937-32-7
Price: $80/20mg
Lycopsamine

Catalog No: CFN00287
CAS No: 10285-07-1
Price: $ /
Lasiocarpine

Catalog No: CFN00289
CAS No: 303-34-4
Price: $ /
Isoalantolactone

Catalog No: CFN98107
CAS No: 470-17-7
Price: $40/20mg
Notopterol

Catalog No: CFN98563
CAS No: 88206-46-6
Price: $80/20mg
Isoliensinine

Catalog No: CFN99574
CAS No: 6817-41-0
Price: $80/20mg
Paeonol

Catalog No: CFN98926
CAS No: 552-41-0
Price: $30/20mg
Ferruginol

Catalog No: CFN92178
CAS No: 514-62-5
Price: $ / mg
Tags: buy Ethyl cinnamate | Ethyl cinnamate supplier | purchase Ethyl cinnamate | Ethyl cinnamate cost | Ethyl cinnamate manufacturer | order Ethyl cinnamate | Ethyl cinnamate distributor