Structure Identification: |
Chinese Traditional and Herbal Drugs, 2006, 37(10):1447-1450. | Chemical constituents from Chinese mangrove plant Cerbera manghas.[Reference: WebLink] | To investigate the chemical constituents of mangrove plant Cerbera manghas collected in Hainan Province of China. METHODS AND RESULTS: Column chromatography techniques were used for separation and purification of the compounds and extensive spectral analyses including 2D NMR spectrum were employed for structural elucidation. Seven compounds were obtained from leaves of C. manghas, including 3R, 5S, 6S, 7E, 9S-3, 5, 9-trihydroxy-6-methoxy-7-megastigmane (I), blumenol A (II), 3R, 5S, 6R, 7E, 9S-3, 5, 6, 9-tetrahydroxy-7-megastigmane (III), 12β-hydroxyl-5α-pregnane-16-ene-3, 20-dione (IV), 12β-hydroxyl-pregnane-4, 16-diene-3, 20-dione (V), 3β, 12β-dihydroxy-pregnane-16-ene-20-one (VI), 3a, 12β-dihydroxy-pregnane-16-ene-20-one (VII). CONCLUSIONS: Compound I is a new compound named as Euscaphin B and other compounds are isolated from C. manghas for the first time. |
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