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Glyurallin A
Glyurallin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Glyurallin A
Price:
CAS No.: 199331-36-7
Catalog No.: CFN89255
Molecular Formula: C21H20O5
Molecular Weight: 352.38 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The roots of Glycyrrhiza aspera.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Glyurallin A possesses an antigenotoxic effect against carcinogenic N-methyl-N-nitrosourea (MNU) for the first time, it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
In vitro:
Genes Environ. 2017 Jan 6;39:5.
Isolation and characterization of antimutagenic components of Glycyrrhiza aspera against N-methyl-N-nitrosourea.[Pubmed: 28074112 ]
A powdered ethanolic extract of Glycyrrhiza aspera root exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) based on the Ames assay with Salmonella typhimurium TA1535. The aim of this study was to identify the antimutagenic components of the powdered ethanolic extract of G. aspera root.
METHODS AND RESULTS:
The powdered ethanolic extract of G. aspera root was sequentially suspended in n-hexane, carbon tetrachloride, dichloromethane, ethyl acetate, and ethanol, and each solvent soluble fraction and the residue were assayed for antimutagenic activity against MNU in S. typhimurium TA1535. The dichloromethane soluble fraction exhibited the highest antimutagenicity and was fractionated several times by silica gel chromatography. The fraction with the highest antimutagenic activity was further purified using HPLC, and the fractions were assayed for antimutagenicity against MNU in S. typhimurium TA1535. Finally, five components with antimutagenic activity against MNU were identified as Glyurallin A, glyasperin B, licoricidin, 1-methoxyphaseollin, and licoisoflavone B.
CONCLUSIONS:
The five components were demonstrated to possess an antigenotoxic effect against carcinogenic MNU for the first time. It is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
Glyurallin A Description
Source: The roots of Glycyrrhiza aspera.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8378 mL 14.1892 mL 28.3785 mL 56.7569 mL 70.9461 mL
5 mM 0.5676 mL 2.8378 mL 5.6757 mL 11.3514 mL 14.1892 mL
10 mM 0.2838 mL 1.4189 mL 2.8378 mL 5.6757 mL 7.0946 mL
50 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.1351 mL 1.4189 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5676 mL 0.7095 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Pelargonidin-3-O-glucoside chloride

Catalog No: CFN92134
CAS No: 18466-51-8
Price: $490/10mg
Honokiol

Catalog No: CFN99902
CAS No: 35354-74-6
Price: $30/20mg
Neoeriocitrin

Catalog No: CFN92304
CAS No: 13241-32-2
Price: $188/20mg
Secologanic acid

Catalog No: CFN95028
CAS No: 60077-46-5
Price: $318/20mg
3-Epidehydropachymic acid

Catalog No: CFN92738
CAS No: 168293-15-0
Price: $318/5mg
Diallyl disulfide

Catalog No: CFN93237
CAS No: 2179-57-9
Price: $50/20mg
Oroxin A

Catalog No: CFN99712
CAS No: 57396-78-8
Price: $128/20mg
Epimedin A

Catalog No: CFN99939
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Price: $128/20mg
Gartanin

Catalog No: CFN98428
CAS No: 33390-42-0
Price: $318/5mg
Procyanidin B3

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