Gnemonol B | CAS:462636-74-4 | Manufacturer ChemFaces

Gnemonol B

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Gnemonol B Description

Source:	The herbs of Gnetum montanum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Biocontrol Sci. 2007 Mar;12(1):7-14.

Antibacterial activity of stilbene oligomers against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) and their synergism with antibiotics.[Pubmed: 17408003]

METHODS AND RESULTS:
Two resveratrol trimers, Gnemonol B isolated from Gnetum gnemon and gnetin E obtained from the Gnetum species, were found to exhibit strong antibacterial activities against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). The MIC values of Gnemonol B against five strains of VRE and nine strains of MRSA were 12.5 and 6.25 microg/ml, respectively. The MIC values of gnetin E against five strains of VRE and nine strains of MRSA ranged from 12.5 to 25microg/ml. These compounds also showed synergistic effects when used in combination with commercially available antibiotics according to the evaluation method using FIC indices.
CONCLUSIONS:
These findings suggested that the application of the test compounds alone or in combination with antibiotics might be useful in controlling and treating VRE and MRSA infections.

Product Name	Gnemonol B
Price:
CAS No.:	462636-74-4
Catalog No.:	CFN92442
Molecular Formula:	C₅₆H₄₂O₁₂
Molecular Weight:	907.0 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Gnetum montanum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Phenols Compound Library Antifection Inhibitor Library

Description:	Gnemonol B exhibits strong antibacterial activity against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA).
Targets:	Antifection

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.1025 mL	5.5127 mL	11.0254 mL	22.0507 mL	27.5634 mL
5 mM	0.2205 mL	1.1025 mL	2.2051 mL	4.4101 mL	5.5127 mL
10 mM	0.1103 mL	0.5513 mL	1.1025 mL	2.2051 mL	2.7563 mL
50 mM	0.0221 mL	0.1103 mL	0.2205 mL	0.441 mL	0.5513 mL
100 mM	0.011 mL	0.0551 mL	0.1103 mL	0.2205 mL	0.2756 mL

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CFN98469	Caraphenol A	354553-35-8	676.7	C₄₂H₂₈O₉
CFN97082	Viniferol D	625096-18-6	680.7	C₄₂H₃₂O₉
CFN95778	Suffruticosol A	220936-82-3	680.7	C₄₂H₃₂O₉
CFN95779	Suffruticosol B	220936-87-8	680.7	C₄₂H₃₂O₉
CFN95780	Suffruticosol C	220936-94-7	680.7	C₄₂H₃₂O₉
CFN96132	Mulberrofuran C	77996-04-4	580.6	C₃₄H₂₈O₉
CFN92788	Mulberrofuran G	87085-00-5	562.6	C₃₄H₂₆O₈
CFN96253	Mulberrofuran G pentaacetate	99217-75-1	772.8	C₄₄H₃₆O₁₃
CFN96881	Mulberrofuran K	94617-36-4	628.67	C₃₉H₃₂O₈