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Gopherenediol
Gopherenediol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Gopherenediol
Price:
CAS No.: 916236-79-8
Catalog No.: CFN96287
Molecular Formula: C20H34O2
Molecular Weight: 306.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Euphorbia lathyris.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Gopherenediol shows weak antifeedant activity.
In vitro:
Springer US,2005 :409-416
Cottontails and gopherweed: Anti-feeding compounds from a spurge[Reference: WebLink]
Mammalian herbivores nearly never attack gopherweed, Euphorbia lathyris (Euphorbiaceae). To find the chemical principle responsible for the deterrent effect, we field-tested plant extracts in response-guided bioassays for antifeedant activity.
METHODS AND RESULTS:
We treated winter-dormant apple twigs with extract solutions and presented them to free-ranging eastern cottontails, Sylvilagus floridanus, at 3 different home ranges in Upstate New York during late winter. Extracts from all plant parts reduced feeding, measured as twig tips cut and amount of bark removed, but root extracts were most active. The bioassay led to isolation of putative antifeedant compounds from the root extract, a series of long-chain alkyl ferulates and Gopherenediol, a new diterpenoid.
CONCLUSIONS:
Bioassay of docosanyl ferulate and Gopherenediol demonstrated weak antifeedant activity. The bioassays are continuing.
Gopherenediol Description
Source: The roots of Euphorbia lathyris.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2626 mL 16.3132 mL 32.6264 mL 65.2529 mL 81.5661 mL
5 mM 0.6525 mL 3.2626 mL 6.5253 mL 13.0506 mL 16.3132 mL
10 mM 0.3263 mL 1.6313 mL 3.2626 mL 6.5253 mL 8.1566 mL
50 mM 0.0653 mL 0.3263 mL 0.6525 mL 1.3051 mL 1.6313 mL
100 mM 0.0326 mL 0.1631 mL 0.3263 mL 0.6525 mL 0.8157 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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