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Mayumbine
Mayumbine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Mayumbine
Price:
CAS No.: 25532-45-0
Catalog No.: CFN98283
Molecular Formula: C21H24N2O3
Molecular Weight: 352.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Rauvolfia vomitoria
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Our products had been exported to the following research institutions and universities, And still growing.
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Molecular Biology Institute of ... (Spain)
  • Universidad de La Salle (Mexico)
  • University of Queensland (Australia)
  • University of Canterbury (New Zealand)
  • University of Oslo (Norway)
  • National Chung Hsing University (Taiwan)
  • Chang Gung University (Taiwan)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Mayumbine (IC50 = 76 ± 3.5 nM) potently inhibit the in vitro binding of 3H-diazepam to the benzodiazepine sites within the rat GABAA receptor complex.
Targets: GABA Receptor
In vitro:
Natural Product Letters.1997;11(1):73-76.
The Heteroyohimbine Mayumbine Binds with High Affinity to Rat Brain Benzodiazepine Receptors in vitro.[Reference: WebLink]

METHODS AND RESULTS:
Mayumbine, a naturally occurring heteroyohimbine, was isolated from Rauwolfia vomitoria extracts and shown to potently (IC50 = 76 ± 3.5 nM) inhibit the in vitro binding of 3H-diazepam to the benzodiazepine sites within the rat GABAA receptor complex.
Mayumbine Description
Source: The herbs of Rauvolfia vomitoria
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8377 mL 14.1884 mL 28.3768 mL 56.7537 mL 70.9421 mL
5 mM 0.5675 mL 2.8377 mL 5.6754 mL 11.3507 mL 14.1884 mL
10 mM 0.2838 mL 1.4188 mL 2.8377 mL 5.6754 mL 7.0942 mL
50 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.1351 mL 1.4188 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5675 mL 0.7094 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN99867Serpentine18786-24-8349.4 C21H21N2O3
CFN96746Rauvotetraphylline E1422506-53-3335.4C20H19N2O3
CFN97709Alstonine642-18-2349.4C21H21N2O3
CFN97710Akuammigine642-17-1352.43C21H24N2O3
CFN97721Serpentinic acid605-14-1335.38C20H19N2O3
CFN98283Mayumbine25532-45-0352.4 C21H24N2O3
CFN98499Serpentinine36519-42-3684.8 C42H44N4O5
CFN986524,R-ajmalicine N-oxide41590-29-8368.4 C21H24N2O4
CFN98760Aricine482-91-7382.5 C22H26N2O4
CFN98761Ajmalicine483-04-5352.4 C21H24N2O3
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