Science | Nature | Cell | View More
Natural Products
Methyl 3-carbazolecarboxylate
Methyl 3-carbazolecarboxylate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Methyl 3-carbazolecarboxylate
Price:
CAS No.: 97931-41-4
Catalog No.: CFN97559
Molecular Formula: C14H11NO2
Molecular Weight: 225.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Yellow powder
Source: The herbs of Micromelum sp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Vigo (Spain)
  • Worcester Polytechnic Institute (USA)
  • Seoul National University of Sc... (Korea)
  • Istanbul University (Turkey)
  • University of Toulouse (France)
  • Fraunhofer-Institut für Moleku... (Germany)
  • University of British Columbia (Canada)
  • Shanghai Institute of Organic C... (China)
  • University of Lodz (Poland)
  • University of Maryland School o... (USA)
  • University of Vienna (Austria)
  • More...
Package
Featured Products
beta-Amyrin

Catalog No: CFN98935
CAS No: 559-70-6
Price: $ /
Tanshinone I

Catalog No: CFN98953
CAS No: 568-73-0
Price: $30/20mg
o-Methoxycinnamaldehyde

Catalog No: CFN93299
CAS No: 1504-74-1
Price: $40/20mg
Proanthocyanidins

Catalog No: CFN99556
CAS No: 4852-22-6
Price: $70/20mg
Meloside A

Catalog No: CFN90132
CAS No: 60767-80-8
Price: $238/5mg
Rebaudioside B

Catalog No: CFN90470
CAS No: 58543-17-2
Price: $138/20mg
Hinokiflavone

Catalog No: CFN92007
CAS No: 19202-36-9
Price: $288/20mg
Adenine

Catalog No: CFN89041
CAS No: 73-24-5
Price: $30/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Ganoderenic acid D

Catalog No: CFN90300
CAS No: 100665-43-8
Price: $368/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Methyl 3-carbazolecarboxylate is a natural product from Micromelum sp.
Targets: Immunology & Inflammation related
In vitro:
Planta Med. 2005 Mar;71(3):261-7.
Anti-tuberculosis constituents from the stem bark of Micromelum hirsutum.[Pubmed: 15770548 ]

METHODS AND RESULTS:
Anti-TB bioassay-directed fractionation led to the isolation of six carbazole alkaloids, as well as the gamma-lactone derivative of oleic acid, from the CH (2)Cl (2) extract of the stem bark of Micromelum hirsutum. The carbazoles include the new micromeline ( 2) and five known alkaloids: lansine ( 3), 3-methylcarbazole ( 4), methyl carbazole-3-carboxylate ( Methyl 3-carbazolecarboxylate,5), 3-formylcarbazole ( 6), and 3-formyl-6-methoxycarbazole ( 7). Compound 1 was identified as the lactone derivative of oleic acid, (-)- Z-9-octadecene-4-olide, for which the trivial name micromolide ( 1) is suggested. It showed potent in vitro anti-TB activity against H37R v (MIC: 1.5 microg/mL), a selectivity index (SI) of 63, and exhibited activity against the Erdman strain of M. tuberculosis in a J774 mouse macrophage model (EC (90) : 5.6 microg/mL).
CONCLUSIONS:
Thus, 1 appears worthy of further evaluation as a potential new anti-TB agent. Isolates 2, 3, 6 and 7 had anti-TB MIC values between 14.3 and 42.3 microg/mL, while compounds 4 and 5 were considered inactive (MIC > 128 microg/mL). Structure elucidation and identification were based on spectroscopic analysis, including MS, 1D/2D NMR, and a full (1)H spin system analysis of 1.
Methyl 3-carbazolecarboxylate Description
Source: The herbs of Micromelum sp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Maingayone B

Catalog No: CFN95483
CAS No: 1071223-57-8
Price: $318/20mg
11beta,13-Dihydrolactucin

Catalog No: CFN95433
CAS No: 83117-63-9
Price: $318/10mg
(-)-Epiafzelechin 3-O-gallate

Catalog No: CFN95081
CAS No: 108907-43-3
Price: $388/5mg
Apigenin 4'-O-(2'',6''-di-O-E-p-co...

Catalog No: CFN95276
CAS No: 71781-79-8
Price: $318/10mg
1-Phenylethyl beta-D-glucoside

Catalog No: CFN95574
CAS No: 93199-03-2
Price: $318/5mg
Momordicine V

Catalog No: CFN95164
CAS No: 1012315-36-4
Price: $463/5mg
11alpha-hydroxy-3,7-dioxo-5alpha-l...

Catalog No: CFN95592
CAS No: 1245703-70-1
Price: $413/5mg
Puerol B

Catalog No: CFN95155
CAS No: 112343-17-6
Price: $398/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4405 mL 22.2025 mL 44.405 mL 88.8099 mL 111.0124 mL
5 mM 0.8881 mL 4.4405 mL 8.881 mL 17.762 mL 22.2025 mL
10 mM 0.444 mL 2.2202 mL 4.4405 mL 8.881 mL 11.1012 mL
50 mM 0.0888 mL 0.444 mL 0.8881 mL 1.7762 mL 2.2202 mL
100 mM 0.0444 mL 0.222 mL 0.444 mL 0.8881 mL 1.1101 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
beta-Amyrin

Catalog No: CFN98935
CAS No: 559-70-6
Price: $ /
Tanshinone I

Catalog No: CFN98953
CAS No: 568-73-0
Price: $30/20mg
o-Methoxycinnamaldehyde

Catalog No: CFN93299
CAS No: 1504-74-1
Price: $40/20mg
Proanthocyanidins

Catalog No: CFN99556
CAS No: 4852-22-6
Price: $70/20mg
Meloside A

Catalog No: CFN90132
CAS No: 60767-80-8
Price: $238/5mg
Rebaudioside B

Catalog No: CFN90470
CAS No: 58543-17-2
Price: $138/20mg
Hinokiflavone

Catalog No: CFN92007
CAS No: 19202-36-9
Price: $288/20mg
Adenine

Catalog No: CFN89041
CAS No: 73-24-5
Price: $30/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Ganoderenic acid D

Catalog No: CFN90300
CAS No: 100665-43-8
Price: $368/20mg
Tags: buy Methyl 3-carbazolecarboxylate | Methyl 3-carbazolecarboxylate supplier | purchase Methyl 3-carbazolecarboxylate | Methyl 3-carbazolecarboxylate cost | Methyl 3-carbazolecarboxylate manufacturer | order Methyl 3-carbazolecarboxylate | Methyl 3-carbazolecarboxylate distributor