Science | Nature | Cell | View More
Natural Products
Minumicrolin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Minumicrolin
Price:
CAS No.: 88546-96-7
Catalog No.: CFN97453
Molecular Formula: C15H16O5
Molecular Weight: 276.3 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The herbs of Murraya exotica L
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Hamdard University (India)
  • Kyushu University (Japan)
  • Colorado State University (USA)
  • Vin?a Institute of Nuclear Scie... (Serbia)
  • University of Leipzig (Germany)
  • Griffith University (Australia)
  • Northeast Normal University Cha... (China)
  • Universidade Católica Portuguesa (Portugal)
  • University of Padjajaran (Indonesia)
  • The Institute of Cancer Research (United Kingdom)
  • University of Stirling (United Kingdom)
  • More...
Package
Featured Products
Decursinol angelate

Catalog No: CFN93173
CAS No: 130848-06-5
Price: $ / mg
Baicalein

Catalog No: CFN98783
CAS No: 491-67-8
Price: $40/20mg
Galangin

Catalog No: CFN98918
CAS No: 548-83-4
Price: $40/20mg
alpha-Mangostin

Catalog No: CFN97050
CAS No: 6147-11-1
Price: $40/20mg
Tetrahydrocurcumin

Catalog No: CFN90583
CAS No: 36062-04-1
Price: $30/20mg
Sodium Danshensu

Catalog No: CFN99163
CAS No: 67920-52-9
Price: $40/20mg
Norisoboldine

Catalog No: CFN99528
CAS No: 23599-69-1
Price: $98/20mg
Quercetin 3,5,7,3,4-pentamethyl et...

Catalog No: CFN70262
CAS No: 1247-97-8
Price: $ / mg
epsilon-Viniferin

Catalog No: CFN97067
CAS No: 62218-08-0
Price: $338/10mg
Kaempferol 7-O-rhamnoside

Catalog No: CFN96224
CAS No: 20196-89-8
Price: $338/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Minumicrolin is a plant growth inhibitor against the 2nd leaf sheath elongation of rice seedlings. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100, it might be valuable anti-tumor-promoting agents. Minumicrolin shows mild butyrylcholinesterase inhibition activity.
In vitro:
Cancer Lett. 1999 Apr 26;138(1-2):87-92.
Anti-tumor-promoting effects of 8-substituted 7-methoxycoumarins on Epstein-Barr virus activation assay.[Pubmed: 10378778 ]

METHODS AND RESULTS:
In a search for anti-tumor-promoting agents, we carried out a primary screening of twenty-nine 8-substituted and four 6-substituted derivatives of 7-methoxycoumarins isolated from plants of the Murraya and/or Citrus species (Rutaceae), examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. This investigation indicated that the prenyl (3-methyl-2-butenyl) or 2-hydroxy-3-methylbutyl (or butenyl) unit as an isoprenoid moiety at C-8 on the 7-methoxycoumarin nucleus plays an important role in the anti-tumor-promoting activity.
CONCLUSIONS:
Some of the 8-substituted 7-methoxycoumarins isolated from Murraya species, murrangatin (7), Minumicrolin (10) and chloticol (18), were found to significantly inhibit EBV-EA activation, and preserved the high viability of Raji cells, suggesting that 7, 10 and 18 might be valuable anti-tumor-promoting agents.
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):515-9.
Two new coumarins from Murraya paniculata.[Pubmed: 18470803 ]

METHODS AND RESULTS:
Two new coumarins, murrmeranzin (1) and murralonginal (2), together with four known compounds Minumicrolin (3), murrangatin (4), meranzin hydrate (5) and hainanmurpanin (6) have been isolated from the aerial parts of Murraya paniculata. The structures of these compounds were determined through spectral analysis.
CONCLUSIONS:
Minumicrolin (3) showed mild butyrylcholinesterase inhibition activity.
Biosci Biotechnol Biochem. 2000 Feb;64(2):420-3.
Coumarin-related compounds as plant growth inhibitors from two rutaceous plants in Thailand.[Pubmed: 10737204 ]

METHODS AND RESULTS:
Chemical investigation of naturally occurring plant growth inhibitors from Rutaceous plants in Thailand led us to identify five 7-methoxycoumarins and one 5,7-dimethoxycoumarin from Murraya paniculata, and six furanocoumarins from Citrus aurantifolia.
CONCLUSIONS:
Of these compounds, murranganon senecioate (1) is a new natural compound found in M. paniculata. Minumicrolin (6) was found to be highly active against the 2nd leaf sheath elongation of rice seedlings.
Minumicrolin Description
Source: The herbs of Murraya exotica L
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
6-Methoxyfraxinellone

Catalog No: CFN95485
CAS No: N/A
Price: $318/10mg
Rhamnocitrin 3-galactoside

Catalog No: CFN95474
CAS No: 99878-05-4
Price: $318/10mg
Neoorthosiphol A

Catalog No: CFN95447
CAS No: 243448-72-8
Price: $318/10mg
Ganoderic acid GS-3

Catalog No: CFN95518
CAS No: 1206781-66-9
Price: $413/5mg
Naringin 4'-glucoside

Catalog No: CFN95014
CAS No: 17257-21-5
Price: $338/5mg
Quercetin 3-O-beta-(6''-p-coumaroy...

Catalog No: CFN95088
CAS No: 143061-65-8
Price: $338/10mg
Arvenin III

Catalog No: CFN95327
CAS No: 65597-45-7
Price: $318/5mg
Pd-C-II

Catalog No: CFN95003
CAS No: N/A
Price: $358/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6193 mL 18.0963 mL 36.1925 mL 72.3851 mL 90.4814 mL
5 mM 0.7239 mL 3.6193 mL 7.2385 mL 14.477 mL 18.0963 mL
10 mM 0.3619 mL 1.8096 mL 3.6193 mL 7.2385 mL 9.0481 mL
50 mM 0.0724 mL 0.3619 mL 0.7239 mL 1.4477 mL 1.8096 mL
100 mM 0.0362 mL 0.181 mL 0.3619 mL 0.7239 mL 0.9048 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Arch Pharm Res. 2011 Apr;34(4):527-31.
C-7 oxygenated coumarins from the fruits of Micromelum minutum.[Pubmed: 21544717 ]

METHODS AND RESULTS:
A new 7-oxygenated coumarin, 7-demethylmurralonginol isovalerate (1), and a new natural product, murralonginol (2), together with seven known 7-oxygenated coumarins, murralonginol isovalerate (3), murralongin (4), micromelin (5), scopoletin (6), microminutin (7), murrangatin (8), and Minumicrolin (9), were isolated from the fruits of Micromelum minutum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data.
CONCLUSIONS:
Among these isolates, compounds 2 and 4 - 9 exhibited cytotoxicity against cholangiocarcinoma cell line, KKU-100.
Decursinol angelate

Catalog No: CFN93173
CAS No: 130848-06-5
Price: $ / mg
Baicalein

Catalog No: CFN98783
CAS No: 491-67-8
Price: $40/20mg
Galangin

Catalog No: CFN98918
CAS No: 548-83-4
Price: $40/20mg
alpha-Mangostin

Catalog No: CFN97050
CAS No: 6147-11-1
Price: $40/20mg
Tetrahydrocurcumin

Catalog No: CFN90583
CAS No: 36062-04-1
Price: $30/20mg
Sodium Danshensu

Catalog No: CFN99163
CAS No: 67920-52-9
Price: $40/20mg
Norisoboldine

Catalog No: CFN99528
CAS No: 23599-69-1
Price: $98/20mg
Quercetin 3,5,7,3,4-pentamethyl et...

Catalog No: CFN70262
CAS No: 1247-97-8
Price: $ / mg
epsilon-Viniferin

Catalog No: CFN97067
CAS No: 62218-08-0
Price: $338/10mg
Kaempferol 7-O-rhamnoside

Catalog No: CFN96224
CAS No: 20196-89-8
Price: $338/10mg
Tags: buy Minumicrolin | Minumicrolin supplier | purchase Minumicrolin | Minumicrolin cost | Minumicrolin manufacturer | order Minumicrolin | Minumicrolin distributor