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Momordin IIa
Momordin IIa
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Momordin IIa
Price:
CAS No.: 95851-50-6
Catalog No.: CFN92563
Molecular Formula: C48H76O18
Molecular Weight: 941.1 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The fruits of Momordica cochinchinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Momordin IIa is a natural product from Momordica cochinchinensis.
Momordin IIa Description
Source: The fruits of Momordica cochinchinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0626 mL 5.3129 mL 10.6259 mL 21.2517 mL 26.5647 mL
5 mM 0.2125 mL 1.0626 mL 2.1252 mL 4.2503 mL 5.3129 mL
10 mM 0.1063 mL 0.5313 mL 1.0626 mL 2.1252 mL 2.6565 mL
50 mM 0.0213 mL 0.1063 mL 0.2125 mL 0.425 mL 0.5313 mL
100 mM 0.0106 mL 0.0531 mL 0.1063 mL 0.2125 mL 0.2656 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry, 1988 , 27 (11) :3585-3591.
Saponins from roots of Momordica cochinchinensis[Reference: WebLink]

METHODS AND RESULTS:
Ten minor saponins, momordin Ia, momordin Ib, Imomordin Ic, momordin Id, momordin Ie and Momordin IIa, momordin IIb, momordin IIc, momordin IId, momordin IIe, were isolated from the root of Momordica cochinchinensis, along with the known major saponins, momordin I and momordin II. Their structures were established on the basis of chemical and spectroscopic analysis. The structures of the two new saponins were assigned as 3β-{([O-β-d-xylopyranosyl-(1→2)-O-β-d-xylopyranosyl-(1→3)]-O-β-d-glucopyranuronosyl)oxy}-olean-12-ene-28-oic acid for momordin Id and momordin Id-28-β-d-glucopyranosyl ester for momordin IId.
CONCLUSIONS:
It was confirmed that the genuine saponin present in the root was not the monodesmoside but the bisdesmoside, though the former is the major component in the dry root.
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