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Monocrotaline N-oxide
Monocrotaline N-oxide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Monocrotaline N-oxide
Price:
CAS No.: 35337-98-5
Catalog No.: CFN00385
Molecular Formula: C16H23NO7
Molecular Weight: 341.36 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Crotalaria pallida Ait.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Monocrotaline N-oxide is an adequate precursor for the production of the courtship pheromone hydroxydanaidal, it is a phagostimulant for larvae and it stimulates the growth and development of adult male androconial organs called coremata.Monocrotaline N-oxide fed to larvae also affects the courtship behavior of adult males.
In vivo:
Journal of Insect Science , 2005 , 5 (1) :1-6.
If you've got it, flaunt it: ingested alkaloids affect corematal display behavior in the salt marsh moth, Estigmene acrea.[Pubmed: 16299591]
Plant-derived pyrrolizidine alkaloids play an important role in the biology of the salt marsh moth, Estigmene acrea (Lepidoptera: Arctiidae). They are phagostimulants for larvae and they stimulate the growth and development of adult male androconial organs called coremata.
METHODS AND RESULTS:
In this study, we have shown that the pyrrolizidine alkaloid Monocrotaline N-oxide (MNO) fed to larvae also affects the courtship behavior of adult males. Males fed a diet containing MNO display their coremata while males fed on the same diet without alkaloid rarely display. This explains why it has been difficult to replicate field observations of the "lekking" behavior of this species in the laboratory where animals are frequently raised on commercially available diets devoid of alkaloids. Corematal inflation was observed in isolated males and in laboratory leks.
CONCLUSIONS:
The effect of larvae feeding on pyrrolizidine alkaloid on the reproductive behavior of adults suggests that this substance may modify the development of the moth's nervous system and contribute to their unusual dual mating strategies. MNO was also shown to be an adequate precursor for the production of the courtship pheromone hydroxydanaidal.
Monocrotaline N-oxide Description
Source: The herbs of Crotalaria pallida Ait.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Nature Plants. 2016 Dec 22;3: 16206.
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PMID: 28005066

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doi: 10.1126/sciadv.aat6994.
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PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9295 mL 14.6473 mL 29.2946 mL 58.5892 mL 73.2365 mL
5 mM 0.5859 mL 2.9295 mL 5.8589 mL 11.7178 mL 14.6473 mL
10 mM 0.2929 mL 1.4647 mL 2.9295 mL 5.8589 mL 7.3236 mL
50 mM 0.0586 mL 0.2929 mL 0.5859 mL 1.1718 mL 1.4647 mL
100 mM 0.0293 mL 0.1465 mL 0.2929 mL 0.5859 mL 0.7324 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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