Mulberrofuran A | CAS:68978-04-1 | Manufacturer ChemFaces

Mulberrofuran A

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Description:

Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE).

Targets:

COX

In vitro:

Chem. Pharm. Bull., 1986, 34(3):1223-7

Effects of flavonoids and related compounds from mulberry tree on arachidonate metabolism in rat platelet homogenates[Pubmed: 3089631]

The effects of various flavonoids and related compounds isolated from the root bark of mulberry tree on rat platelet lipoxygenase and cyclooxygenase products formed from [1-14C] arachidonic acid were studied.
METHODS AND RESULTS:
Morusin was found to inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products) more strongly than the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product). Oxydihydromorusin and kuwanon C were also found to inhibit the formation of thromboxane B2 more strongly than the formations of HHT and 12-HETE.
CONCLUSIONS:
Mulberrofuran A inhibited the formations of HHT and thromboxane B2, but it increased the formation of 12-HETE. Albanol B and mulberrofuran F did not affect arachidonate metabolism in rat platelet homogenates.arachidonate metabolism in rat platelet homogenates.

Mulberrofuran A Description

Source:	The root barks of Morus alba L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Mulberrofuran A
Price:
CAS No.:	68978-04-1
Catalog No.:	CFN92772
Molecular Formula:	C₂₅H₂₈O₄
Molecular Weight:	392.5 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The root barks of Morus alba L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-platelet aggregation Compound Library Phenols Compound Library COX Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5478 mL	12.7389 mL	25.4777 mL	50.9554 mL	63.6943 mL
5 mM	0.5096 mL	2.5478 mL	5.0955 mL	10.1911 mL	12.7389 mL
10 mM	0.2548 mL	1.2739 mL	2.5478 mL	5.0955 mL	6.3694 mL
50 mM	0.051 mL	0.2548 mL	0.5096 mL	1.0191 mL	1.2739 mL
100 mM	0.0255 mL	0.1274 mL	0.2548 mL	0.5096 mL	0.6369 mL

CFN97198	Canniprene	70677-47-3	342.4	C₂₁H₂₆O₄
CFN90824	4'-Prenyloxyresveratrol	69065-16-3	312.4	C₁₉H₂₀O₄
CFN92323	Chlorophorin	537-41-7	380.5	C₂₄H₂₈O₄
CFN92772	Mulberrofuran A	68978-04-1	392.5	C₂₅H₂₈O₄
CFN97178	Moracin C	69120-06-5	310.4	C₁₉H₁₈O₄
CFN97507	5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol	936006-11-0	310.4	C₁₉H₁₈O₄
CFN97179	Moracin D	69120-07-6	308.3	C₁₉H₁₆O₄
CFN92326	Moracin T	1146113-27-0	340.4	C₂₀H₂₀O₅
CFN92324	Moracin P	102841-46-3	326.4	C₁₉H₁₈O₅
CFN99587	Mulberroside C	102841-43-0	458.46	C₂₄H₂₆O₉